| |
H6PD rs6688832:G>A polymorphism
|
F/P*
|
P†
|
|---|
|
G/G (n = 464)
|
G/A (n = 377)
|
A/A (n = 83)
|
|---|
|
Age (years)
|
59.0 ± 10.3
|
58.0 ± 10.6
|
56.7 ± 10.4
|
–
|
0.125
|
|
Males (%)
|
44.2
|
44.0
|
38.6
|
–
|
0.621
|
|
T2DM duration (years)
|
11 (1–47)
|
10 (1–51)
|
10 (1–48)
|
–
|
0.043
|
|
Systolic BP (mmHg)a
|
135.4 ± 21.3
|
136.9 ± 22.2
|
136.0 ± 24.0
|
1.401/0.242
|
–
|
|
Diastolic BP (mmHg)a
|
83.4 ± 11.2
|
85.0 ± 13.5
|
84.7 ± 13.0
|
2.656/0.071
|
–
|
|
Body mass index (kg/m2)b
|
29.1 ± 5.2
|
29.4 ± 5.4
|
28.6 ± 5.2
|
1.647/0.193
|
–
|
|
Waist circumference (cm)b
|
98.6 ± 12.6
|
98.5 ± 11.9
|
98.7 ± 10.7
|
0.003/0.997
|
–
|
|
HbA1c (%)
|
7.1 ± 2.1
|
7.2 ± 2.1
|
7.4 ± 2.3
| |
0.196
|
|
Total cholesterol (mg/dL)c
|
208.8 ± 50.3
|
204.9 ± 42.5
|
220.4 ± 42.5
|
1.353/0.261
|
–
|
|
HDL cholesterol (mg/dL)c
|
46.4 ± 15.5
|
46.4 ± 11.6
|
46.4 ± 11.6
|
1.339/0.264
|
–
|
|
LDL cholesterol (mg/dL)a
|
131.5 ± 54.1
|
131.5 ± 42.5
|
3.7 ± 38.7
|
0.657/0.520
|
–
|
|
Triglycerides (mg/dL)c
|
150.7 (26.6–1470.3)
|
141.7 (0.3–1240.0)
|
150.7 (53.1–469.4)
|
0.414/0.661
|
–
|
|
MetS (%)
|
74.4
|
76.7
|
75.4
|
–
|
0.790
|
- Data expressed as mean ± SD, median (range), or %
- BP blood pressure, MetS metabolic syndrome, T2DM type 2 diabetes mellitus, HbA1c glycated hemoglobin
- * F and P values obtained from the general linear model univariate analyses, after adjusting for: aage and gender, use of medication for hypertension, and BMI; bage and gender; cage, gender, use of hypolipidemic medications
- †P values were computed by χ2 test or ANOVA as appropriate. Only P values lower than the Bonferroni threshold (0.0055) were considered statistically significant
