Table 1 Clinical and laboratory characteristics of T2DM patients according to genotypes of the HSD11B1 rs45487298:delA>insA polymorphism

Age (years)

58.5 ± 10.6

58.2 ± 10.0

57.3 ± 8.9

–

0.642

Males (%)

42.8

43.4

54.5

–

0.415

T2DM duration (years)

10.0 (1–48)

10.0 (1–51)

12.5 (1–46)

–

0.330

Systolic BP (mmHg)^a

137.7 ± 22.6

133.1 ± 20.2

131.0 ± 13.8

2.952/0.053

–

Diastolic BP (mmHg)^a

84.7 ± 12.2

83.3 ± 12.8

83.0 ± 7.6

0.591/0.554

–

Body mass index (kg/m²)^b

29.2 ± 5.0

29.3 ± 5.6

28.4 ± 4.9

0.250/0.778

–

Waist circumference (cm)^b

98.7 ± 12.3

98.7 ± 11.6

100.8 ± 14.4

0.141/0.868

–

HbA1c (%)

7.2 ± 2.1

7.4 ± 2.1

7.3 ± 2.3

0.909

Total cholesterol (mg/dL)^b

208.8 ± 46.4

208.8 ± 50.3

193.3 ± 54.1

0.682/0.384

–

HDL cholesterol (mg/dL)^c

46.4 ± 11.6

50.3 ± 11.6

42.5 ± 19.3

2.488/0.116

–

LDL cholesterol (mg/dL)^c

135.3 ± 50.3

131.5 ± 50.3

112.1 ± 23.2

1.889/0.155

–

Triglycerides (mg/dL)^c

141.7 (26.6–1470.3)

150.6 (26.6–779.5)

230.3 (44.3–806.0)

0.280/0.756

–

MetS (%)

78.8

73.4

78.6

–

0.232