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Table 5 Confirmation of risk for GDM in women with and without PCOS stratified by PPBMI in a separate cohort (n = 18106)

From: Early pregnancy metabolic factors associated with gestational diabetes mellitus in normal-weight women with polycystic ovary syndrome: a two-phase cohort study

 

PCOS (n = 877)

Non-PCOS (n = 17,229)

p-value*

Age, years, mean ± SD

31.04 ± 3.44

31.46 ± 4.03

0.0002

Gravidity, mean ± SD

1.73 ± 0.96

1.93 ± 1.10

< 0.0001

PPBMI, kg/m2, mean ± SD

23.52 ± 3.72

21.67 ± 3.11

0.0002

Prevalence of overweight/obesity

266 (30.33)

2265 (13.15)

< 0.0001

Family history of DM, n (%)

164 (18.70)

2057 (11.94)

< 0.0001

Family history of hypertension, n (%)

267 (30.44)

3415 (19.82)

< 0.0001

GDM, n (%)

 < 25 kg/m2

135 (22.09)

2173 (14.52)

< 0.0001

 ≥25 kg/m2

88 (33.08)

718 (31.70)

0.65

 Total

223 (25.43)

2891 (16.78)

< 0.0001

  1. Italic values are statistically significant at p < 0.05
  2. Family history of DM and hypertension means related history of first degree relatives
  3. GDM gestational diabetes, PCOS polycystic ovary syndrome, PPBMI pre-pregnancy body mass index, DM diabetes mellitus, SBP systolic blood pressure
  4. * p-value was calculated by student t-test for numeric variables and by Chi square test for categorical variables