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Table 2 Pregnancy outcomes in women with and without PCOS stratified by PPBMI in the initial cohort

From: Early pregnancy metabolic factors associated with gestational diabetes mellitus in normal-weight women with polycystic ovary syndrome: a two-phase cohort study

 

PPBMI

PCOS (n = 242)

Non-PCOS (n = 324)

p-value*

GDM, n (%)

< 25 kg/m2

39 (26.5)

30 (16.2)

0.02

≥ 25 kg/m2

34 (35.8)

46 (33.1)

0.7

Total

73 (30.2)

76 (23.5)

0.07

PIH + Pre-eclampsia, n (%)

< 25 kg/m2

9 (6.1)

12 (6.5)

0.9

≥ 25 kg/m2

21 (22.1)

30 (21.6)

0.9

Total

30 (12.4)

42 (12.96)

0.8

PIH, n (%)

< 25 kg/m2

6 (4.1)

7 (3.8)

0.9

≥ 25 kg/m2

14 (14.7)

19 (13.7)

0.8

Total

20 (8.3)

26 (8.0)

0.8

Pre-eclampsia, n (%)

< 25 kg/m2

3 (2.0)

5 (2.7)

0.9

≥ 25 kg/m2

7 (7.4)

11 (7.9)

0.9

Total

10 (4.1)

16 (4.9)

0.7

Delivery week, weeks, mean (SD)

< 25 kg/m2

38.8 (1.2)

38.8 (1.3)

0.6

 

≥ 25 kg/m2

38.2 (2.1)

38.5 (1.4)

0.2

 

Total

38.5 (1.7)

38.7 (1.4)

0.2

Preterm delivery, n (%)

< 25 kg/m2

4 (2.7)

1 (0.5)

0.1

≥ 25 kg/m2

8 (8.4)

4 (2.9)

0.07

Total

12 (5.0)

5 (1.5)

0.02

PROM, n (%)

< 25 kg/m2

42 (28.6)

44 (23.8)

0.3

≥ 25 kg/m2

19 (20.0)

34 (24.5)

0.4

Total

61 (25.2)

78 (24.1)

0.8

Birth weight, g, mean (SD)

< 25 kg/m2

3379.7 (507.7)

3454.8 (442.7)

0.2

≥ 25 kg/m2

3407.6 (602.2)

3521.4 (503.8)

0.1

Total

3390.6 (545.7)

3483.8 (407.3)

0.03

LGA, n (%)

< 25 kg/m2

33 (22.5)

36 (19.5)

0.5

≥ 25 kg/m2

28 (29.5)

54 (38.9)

0.14

Total

61 (25.2)

90 (27.8)

0.5

Macrosomia, n (%)

< 25 kg/m2

11 (7.5)

16 (8.7)

0.7

≥ 25 kg/m2

13 (13.7)

20 (14.4)

0.9

Total

24 (9.9)

36 (11.1)

0.6

SGA, n (%)

< 25 kg/m2

4 (2.7)

2 (1.1)

0.18

≥ 25 kg/m2

0 (0.0)

5 (3.6)

0.08

Total

4 (1.7)

7 (2.2)

0.7

Low birth weight, n (%)

< 25 kg/m2

6 (4.1)

4 (2.2)

0.3

≥ 25 kg/m2

5 (5.3)

7 (5.0)

0.9

Total

11 (4.6)

11 (3.4)

0.5

Congenital anomaly, n (%)

< 25 kg/m2

1 (0.7)

2 (1.1)

1

≥ 25 kg/m2

2 (2.1)

0

0.2

Total

3 (1.2)

2 (0.6)

0.7

  1. Italic values are statistically significant at p < 0.05
  2. PCOS polycystic ovary syndrome, PPBMI pre-pregnancy body mass index, GDM gestational diabetes, PIH pregnancy induced hypertension, PROM premature rupture membrane, LGA large for gestational age, SGA small for gestational age, LBW low birth weight
  3. * p-value was calculated by student t-test for numeric variables and by Chi square test for categorical variables