Diabetology & Metabolic Syndrome

Table 1 Biochemical parameters in serum

From: Effect of insulin–glucose metabolism compared with obesity on adipose omentin gene expression in different models of diabetic C57BL/6 mice

Parameters^b	Study groups^a
Parameters^b	Control (Group 1)	T1D (Group 2)	P value	HFD + STZ (Group 3)	P value	NPD + STZ (Group 4)	P value
FBG	6.19 ± 0.6	21.99 ± 6.62	0.000	9.46 ± 0.88	0.000	6.27 ± 0.52	0.805
TG	1.30 ± 0.09	1.67 ± 0.12	0.025	2.16 ± 0.11	0.000	1.81 ± 0.29	0.038
TC	3.51 ± 0.27	3.99 ± 0.38	0.055	7.75 ± 0.67	0.000	4.28 ± 0.70	0.086
LDL	1.45 ± 0.21	1.48 ± 0.14	0.815	1.61 ± 0.12	0.155	1.57 ± 0.21	0.333
HDL	1.16 ± 0.14	1.42 ± 0.11	0.006	2.67 ± 0.65	0.001	1.69 ± 0.29	0.097
AST	170 ± 22.86	343.33 ± 31.41	0.001	137 ± 19.10	0.063	125.42 ± 26.12	0.237
ALT	13 ± 3.22	185 ± 27.92	0.0001	26.85 ± 4.98	0.0001	26 ± 8.83	0.037
Omentin	3.89 ± 0.487	5.65 ± 0.55	0.01	3.26 ± 0.41	0.176	2.01 ± 0.52	0.001
Insulin	2.38 ± 0.65	0.66 ± 0.18	0.022	4.68 ± 0.81	0.038	1.75 ± 0.58	0.159

Significant values are in italics
Values are mean ± SD. Serum parameters are measured on 9th week for group 2, and 12th week for groups 3 and 4
^aControl group: the regular chow (Group 1); T1D: type 1 diabetes (Group 2), HFD + STZ: high fat diet and low dose of STZ (Group 3), NPD + STZ: normal pellet diet and low dose STZ (Group 4)
^bFBG (mmol/L); TG (mmol/L), TC (mmol/L), LDL density lipoprotein (mmol/L), HDL (mmol/L), AST (IU/L), ALT (IU/L), omentin (ng/mL), insulin (μIU/mL)

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