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Table 1 Biochemical parameters in serum

From: Effect of insulin–glucose metabolism compared with obesity on adipose omentin gene expression in different models of diabetic C57BL/6 mice

Parametersb Study groupsa
Control (Group 1) T1D (Group 2) P value HFD + STZ (Group 3) P value NPD + STZ (Group 4) P value
FBG 6.19 ± 0.6 21.99 ± 6.62 0.000 9.46 ± 0.88 0.000 6.27 ± 0.52 0.805
TG 1.30 ± 0.09 1.67 ± 0.12 0.025 2.16 ± 0.11 0.000 1.81 ± 0.29 0.038
TC 3.51 ± 0.27 3.99 ± 0.38 0.055 7.75 ± 0.67 0.000 4.28 ± 0.70 0.086
LDL 1.45 ± 0.21 1.48 ± 0.14 0.815 1.61 ± 0.12 0.155 1.57 ± 0.21 0.333
HDL 1.16 ± 0.14 1.42 ± 0.11 0.006 2.67 ± 0.65 0.001 1.69 ± 0.29 0.097
AST 170 ± 22.86 343.33 ± 31.41 0.001 137 ± 19.10 0.063 125.42 ± 26.12 0.237
ALT 13 ± 3.22 185 ± 27.92 0.0001 26.85 ± 4.98 0.0001 26 ± 8.83 0.037
Omentin 3.89 ± 0.487 5.65 ± 0.55 0.01 3.26 ± 0.41 0.176 2.01 ± 0.52 0.001
Insulin 2.38 ± 0.65 0.66 ± 0.18 0.022 4.68 ± 0.81 0.038 1.75 ± 0.58 0.159
  1. Significant values are in italics
  2. Values are mean ± SD. Serum parameters are measured on 9th week for group 2, and 12th week for groups 3 and 4
  3. aControl group: the regular chow (Group 1); T1D: type 1 diabetes (Group 2), HFD + STZ: high fat diet and low dose of STZ (Group 3), NPD + STZ: normal pellet diet and low dose STZ (Group 4)
  4. bFBG (mmol/L); TG (mmol/L), TC (mmol/L), LDL density lipoprotein (mmol/L), HDL (mmol/L), AST (IU/L), ALT (IU/L), omentin (ng/mL), insulin (μIU/mL)