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Table 4 Effect of single variant on lipid parameters

From: The combined role of allelic variants of IRS-1 and IRS-2 genes in susceptibility to type2 diabetes in the Punjabi Pakistani subjects

Variant

Genotype

TC

TG

HDL

LDL

G972R

GG

5.04 ± 0.06

2.29 ± 0.03

1.48 ± 0.02

2.42 ± 0.03

GR

5.01 ± 0.06

2.21 ± 0.03

1.49 ± 0.02

2.41 ± 0.03

RR

4.96 ± 0.14

2.31 ± 0.07

1.43 ± 0.04

2.45 ± 0.07

p-value

0.877

0.240

0.507

0.897

G1057D

GG

4.97 ± 0.06

2.23 ± 0.03

1.52 ± 0.02

2.39 ± 0.02

GD

5.06 ± 0.07

2.24 ± 0.04

1.47 ± 0.02

2.43 ± 0.03

DD

5.12 ± 0.13

2.52 ± 0.07

1.29 ± 0.04

2.58 ± 0.08

p-value

0.531

0.006

0.000

0.039