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Table 4 Effect of single variant on lipid parameters

From: The combined role of allelic variants of IRS-1 and IRS-2 genes in susceptibility to type2 diabetes in the Punjabi Pakistani subjects

Variant Genotype TC TG HDL LDL
G972R GG 5.04 ± 0.06 2.29 ± 0.03 1.48 ± 0.02 2.42 ± 0.03
GR 5.01 ± 0.06 2.21 ± 0.03 1.49 ± 0.02 2.41 ± 0.03
RR 4.96 ± 0.14 2.31 ± 0.07 1.43 ± 0.04 2.45 ± 0.07
p-value 0.877 0.240 0.507 0.897
G1057D GG 4.97 ± 0.06 2.23 ± 0.03 1.52 ± 0.02 2.39 ± 0.02
GD 5.06 ± 0.07 2.24 ± 0.04 1.47 ± 0.02 2.43 ± 0.03
DD 5.12 ± 0.13 2.52 ± 0.07 1.29 ± 0.04 2.58 ± 0.08
p-value 0.531 0.006 0.000 0.039