Fig. 4From: Myokine–adipokine cross-talk: potential mechanisms for the association between plasma irisin and adipokines and cardiometabolic risk factors in Mexican children with obesity and the metabolic syndromeProposed cross-talk between adipokines and irisin and their contribution to the pathogenesis of MS. Continuous lines indicate an effect that could be observed in context of obesity and MS. Green lines indicate stimulation and red lines indicate inhibition. Dotted red lines indicate a normally present inhibition that may not be present in obesity and MSBack to article page