Table 2 Results of overall and subgroup analyses
Variables | Sample size | Dominant comparison | Recessive comparison | Over-dominant comparison | Allele comparison |
|---|---|---|---|---|---|
p value OR (95% CI) | p value OR (95% CI) | p value OR (95% CI) | p value OR (95% CI) | ||
Overall | 51,656/64,153 | < 0.0001 0.66 (0.63–0.70) | < 0.0001 1.64 (1.56–1.73) | < 0.0001 1.27 (1.21–1.34) | < 0.0001 0.71 (0.68–0.74) |
Caucasian | 19,410/23,456 | < 0.0001 0.64 (0.58–0.70) | < 0.0001 1.64 (1.54–1.75) | < 0.0001 1.31 (1.21–1.43) | < 0.0001 0.70 (0.65–0.75) |
East Asian | 17,607/27,348 | < 0.0001 0.73 (0.63–0.83) | < 0.0001 1.90 (1.46–2.46) | 0.0006 1.28 (1.11–1.48) | < 0.0001 0.74 (0.66–0.83) |
South Asian | 9326/6730 | < 0.0001 0.63 (0.59–0.68) | < 0.0001 1.65 (1.48–1.84) | < 0.0001 1.24 (1.16–1.33) | < 0.0001 0.65 (0.60–0.71) |