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Table 2 Characteristics of 150 control group across the sex-specific quartiles of energy-adjusted NEAP and PRAL score in a case–control study

From: The dietary acid load is higher in subjects with prediabetes who are at greater risk of diabetes: a case–control study

Range

NEAP

Q1 (8.0–26.58)

Q2 (26.66–32.46)

Q3 (32.49–38.3)

Q4 (38.4–89.0)

P-trend

NEAP, median (mEq/day)

23.3

29.1

34.8

42.7

 

No. of subjects

37

38

38

37

 

Sex, n (%)

 Male

12 (8.4)

13 (8.8)

14 (8.4)

12 (8.4)

0.9

 Female

25 (16.7)

25 (16.7)

24 (16.0)

25 (16.7)

 

Age (years)

47.5 ± 7.2

48.1 ± 8.3

46.9 ± 6.8

48.3 ± 6.6

0.8

Education (years)

7.7 ± 4.0

6.5 ± 3.9

7.3 ± 3.5

6.3 ± 3.9

0.2

Dietary supplement use, n (%)

 Yes

5 (3.3)

3 (2.0)

9 (6.0)

3 (2.0)

0.1

 No

32 (21.3)

35 (23.5)

29 (19.3)

34 (22.7)

 

Weight (kg)

67.4 ± 9.7

73.8 ± 9.3

76.0 ± 12.8

72.5 ± 12.0

0.03

Height (cm)

160.4 ± 7.9

163.5 ± 8.4

165.3 ± 8.2

163.7 ± 8.8

0.057

WC (cm)

85.9 ± 9.2

91.3 ± 10.1

88.9 ± 10.0

88.3 ± 9.7

0.4

BMI (kg/m2)

26.2 ± 4.0

27.6 ± 2.9

27.7 ± 4.1

26.9 ± 3.1

0.4

PA (MET/h/week)

1397.5 ± 1193.2

1462.4 ± 1311.1

1606.1 ± 1255.7

1788.5 ± 1105.9

0.1

Energy intake (Kcal/day)

2257.1 ± 595.4

2373.7 ± 543.0

2302.0 ± 625.3

2177.4 ± 752.9

0.5

Systolic blood pressure (mmHg)

119.1 ± 10.5

119.8 ± 10.1

117.6 ± 12.0

116.7 ± 10.9

0.2

Diastolic blood pressure (mmHg)

72.5 ± 7.4

73.8 ± 8.1

74.6 ± 8.0

72.5 ± 7.6

0.8

FBG (mg/dl)

82.8 ± 6.5

82.1 ± 6.9

82.1 ± 7.7

81.5 ± 7.5

0.4

2-h glucose (mg/dl)

121.3 ± 9.0

120.9 ± 9.6

121.0 ± 9.7

118.2 ± 9.7

0.1

PRAL (mEq/day)

− 37.4 ± 19.3

− 21.0 ± 5.1

− 11.4 ± 4.4

0.32.5 ± 9.8

< 0.001

Range

PRAL

Q1 (− 132.7, − 26.54)

Q2 (− 26.52, − 15.07)

Q3 (− 14.8, − 6.87)

Q4 (− 6.86, 32.9)

P-trend

PRAL, median (mEq/day)

− 32.8

− 21.6

− 11.8

− 2.6

 

No. of subjects

38

38

37

37

 

Sex, n (%)

 Male

11 (7.3)

14 (9.3)

11 (7.3)

15 (10.0)

0.6

 Female

27 (18.0)

24 (16.0)

26 (17.3)

22 (14.7)

 

Age (years)

47.8 ± 7.3

47.3 ± 7.8

47.3 ± 7.1

48.4 ± 6.8

0.7

Education (years)

7.1 ± 3.6

7.2 ± 4.1

7.1 ± 4.1

6.3 ± 3.6

0.3

Dietary supplement use, n (%)

 Yes

4 (2.7)

5 (3.3)

7 (4.7)

4 (2.7)

0.6

 No

34 (22.7)

33 (22.0)

30 (20.0)

33 (22.0)

 

Weight (kg)

67.6 ± 9.1

74.3 ± 11.9

73.7 ± 11.4

74.2 ± 11.9

0.01

Height (cm)

160.1 ± 7.7

164.9 ± 9.0

163.6 ± 8.2

164.5 ± 8.4

0.053

WC (cm)

86.7 ± 9.2

89.7 ± 10.8

88.1 ± 9.1

90.1 ± 10.2

0.2

BMI (kg/m2)

26.4 ± 3.8

27.2 ± 3.7

27.5 ± 3.8

27.3 ± 3.1

0.2

PA (MET/h/week)

1600.7 ± 1244.9

1380.6 ± 1218.4

1473.0 ± 1228.4

1803.2 ± 1181.2

0.4

Energy intake (Kcal/day)

2413.1 ± 633.0

2280.8 ± 584.4

2062.1 ± 580.4

2353.9 ± 688.1

0.3

Systolic blood pressure (mmHg)

118.8 ± 10.5

119.6 ± 10.6

118.5 ± 11.6

116.4 ± 10.9

0.3

Diastolic blood pressure (mmHg)

72.7 ± 7.5

73.6 ± 8.2

73.3 ± 7.6

73.7 ± 7.9

0.6

FBG (mg/dl)

83.0 ± 6.6

80.8 ± 6.7

83.1 ± 7.1

81.5 ± 8.0

0.6

2-h glucose (mg/dl)

122.8 ± 8.1

118.5 ± 9.5

123.3 ± 8.7

116.9 ± 10.3

0.057

NEAP (mEq/day)

22.8 ± 4.0

29.8 ± 2.6

35.1 ± 3.3

45.9 ± 12.5

< 0.001

  1. ANOVA and x2 tests were used for continuous and categorical variables, respectively
  2. Energy-adjusted using the residual method
  3. NEAP net endogenous acid production, PRAL potential renal acid load, WC waist circumference, BMI body mass index, PA physical activity, MET metabolic equivalent, FBG fasting blood glucose, NEAP net endogenous acid production
  4. Values are mean ± SD
  5. Number of subjects having the characteristic with %