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Table 3 Clinical, metabolic and cardiovascular autonomic parameters in patients with CGL subdivided into groups with and without left ventricular hypertrophy (n = 10)

From: Association between cardiovascular autonomic neuropathy and left ventricular hypertrophy in young patients with congenital generalized lipodystrophy

Variables

LVH

(n = 4)

No LVH

(n = 6)

P

Female, % (n)

14 (6; 25)

10 (7; 30)

0.665

Age (years)

75 (3)

50 (3)

0.571

pBMI (%)

21.7 (18.7; 22.9)

17.9 (16.2; 22.0)

0.086

Systolic BP (mmHg)

129 (110; 175)

118 (90; 145)

0.394

Diastolic BP (mmHg)

84 (50; 109)

76 (65; 90)

0.392

Basal HR (bpm)

83 (72; 96)

95 (76; 109)

0.136

30/15 coefficient

1.04 (0.98; 1.59)

1.20 (1.13; 1.57)

0.199

Valsalvacoefficient

1.33 (1.15; 1.82)

1.64 (1.29; 2.34)

0.201

E/I coefficient

1.17 (1.09; 1.46)

1.35 (1.27; 1.57)

0.135

Reduction in SBP (mmHg)

11 (6; 22)

3.5 (0; 12)

0.087

Component of very low frequency (Hz)

350 (299; 694)

652 (88; 4250)

0.670

Component of low frequency (Hz)

316 (139; 756)

482 (158; 4294)

0.670

Component of high frequency (Hz)

235 (55; 603)

905 (147; 1840)

0.033

Total amplitude spectrum (Hz)

898 (501; 2054)

2389 (621; 9691)

0.136

LF/HF ratio

1.45 (1.18; 1.69)

0.42 (0.12; 3.7)

0.285

  1. Italic values indicate significance of P value (P < 0.05)
  2. CGL, congenital generalized lipodystrophy; LVH, left ventricular hypertrophy; BMI, body mass index; HR, heart rate; BP, blood pressure; SBP, systolic blood pressure; LF/HF, low frequency/high frequency ratio