Table 2 Echocardiographic, electrocardiographic and carotid Doppler sonography parameters in patients with congenital generalized lipodystrophy and healthy individuals (n = 30)
Variable | CGL (n = 10) | Healthy group (n = 20) | P |
|---|---|---|---|
LVH (%) | 40 (4) | 0 | 0.008 |
LVMI children and adolescents (g/m2.7) | 41.4 (29.2; 89.0) n = 8 | 28.5 (17.1; 37.2) n = 16 | 0.001 |
LVMI adults (g/m2) | 121.9 (89.0; 154.6) n = 2 | 50.4 (41.0; 58.5) n = 4 | 0.064 |
Total LVMI (g/m2.7 or g/m2) | 54.5 (29.2; 154.6) | 29.6 (17.1; 58.5) | 0.002 |
LVDD (mm) | 4 (34; 52) | 43 (33; 52) | 0.791 |
LVSD (mm) | 26 (20; 35) | 26 (19; 36) | 0.507 |
IVS (mm) | 8 (7; 12) | 6 (3; 9) | 0.000 |
LVPW (mm) | 10 (6; 13) | 6 (4; 9) | 0.000 |
Ejection fraction (%) | 70 (59; 76) | 72 (58; 82) | 0.279 |
cIMT (mm) | 0.59 (0.53; 0.75) | 0.52 (0.38; 0.60) | 0.001 |
Right cIMT (mm) | 0.60 (0.50; 0.85) | 0.50 (0.33; 0.60) | 0.007 |
Left cIMT (mm) | 0.61 (0.48; 0.65) | 0.51 (0.40; 0.66) | 0.010 |
cQT interval (s) | 0.43 (0.41; 0.49) | 0.41 (0.38–0.44) | 0.007 |
cQT interval prolongation (%) | 50 (5) | 5 (1) | 0.009 |