Table 4 Association of risk factors for quartile of HOMA-IR in metabolic disorders

Hypertension

 HOMA-IR Q1

Reference^b

0.94 (0.57–1.54)

3.57 (1.89–6.75)

2.44 (0.90––6.60)

 HOMA-IR Q2

1.72 (1.19–2.50)

1.94 (1.19–3.16)

3.73 (2.29–6.06)

3.15 (1.45–6.87)

 HOMA-IR Q3

2.78 (1.98–3.91)

1.50 (0.91–2.48)

3.99 (2.73–5.85)

6.68 (3.73–12.0)

 HOMA-IR Q4

6.69 (4.79–9.34)

4.40 (2.64–7.36)

7.75 (5.39–11.2)

7.44 (4.55–12.2)

 P for trend

0.08

0.03

0.03

0.006

Hypertriglyceridemia

 HOMA-IR Q1

Reference

0.77 (0.49–1.21)

6.52 (3.81–11.1)

3.18 (1.38–7.37)

 HOMA-IR Q2

2.31 (1.69–3.16)

1.37 (0.86–2.18)

8.38 (5.56–12.6)

4.90 (2.58–9.34)

 HOMA-IR Q3

5.92 (4.45–7.87)

2.29 (1.53–3.42)

17.0 (12.2–23.7)

6.37 (3.68–11.0)

 HOMA-IR Q4

9.48 (7.05–12.8)

3.22 (1.98–5.23)

18.8 (13.4–26.4)

4.43 (2.74–7.15)

 P for trend

0.02

0.02

0.004

0.11

High LDL-c

 HOMA-IR Q1

Reference

1.15 (0.84–1.58)

2.60 (1.54–4.37)

2.90 (1.39–6.01)

 HOMA-IR Q2

1.28 (0.98–1.66)

1.31 (0.90–1.90)

2.96 (2.02–4.35)

2.01 (1.06–3.83)

 HOMA-IR Q3

2.29 (1.80–2.91)

1.39 (0.98–1.97)

3.55 (2.67–4.73)

4.70 (2.80–7.90)

 HOMA-IR Q4

4.64 (3.61–5.97)

2.59 (1.68–3.99)

5.01 (3.75–6.69)

6.97 (4.50–10.8)

 P for trend

0.07

0.07

0.005

0.03

Hyperuricemia

 HOMA-IR Q1

Reference

1.14 (0.82–1.59)

2.53 (1.48–4.32)

3.19 (1.52–6.70)

 HOMA-IR Q2

1.25 (0.95–1.65)

1.10 (0.73–1.66)

2.95 (2.00–4.37)

2.74 (1.47–5.14)

 HOMA-IR Q3

2.56 (2.00–3.28)

1.64 (1.14–2.34)

4.19 (3.13–5.61)

3.33 (1.96–5.68)

 HOMA-IR Q4

4.96 (3.83–6.42)

2.15 (1.36–3.38)

6.45 (4.80–8.67)

6.21 (4.02–9.58)

 P for trend

0.06

0.03

0.005

0.04

Metabolic symptoms

 HOMA-IR Q1

Reference

0.27 (0.10–0.80)

10.5 (5.50–19.9)

2.44 (0.70–8.56)

 HOMA-IR Q2

2.55 (1.60–4.08)

0.74 (0.30–1.81)

9.15 (5.35–15.6)

7.06 (3.17–15.7)

 HOMA-IR Q3

9.62 (6.34–14.6)

3.62 (2.11–6.23)

24.0 (15.5–37.3)

9.17 (4.71–17.9)

 HOMA-IR Q4

27.4 (18.0–41.7)

8.34 (4.67–14.9)

46.0 (29.5–71.8)

23.2 (13.4–40.1)

 P for trend

0.08

0.07

0.02

0.03

High ALT level

 HOMA-IR Q1

Reference

1.68 (1.27–2.21)

2.22 (1.33–3.73)

2.71 (1.32–5.58)

 HOMA-IR Q2

1.17 (0.78–1.28)

1.70 (1.22–2.36)

2.10 (1.42–3.09)

3.19 (1.75–5.80)

 HOMA-IR Q3

2.01 (1.60–2.53)

2.23 (1.63–3.05)

2.79 (2.11–3.70)

3.22 (1.92–5.40)

 HOMA-IR Q4

4.87 (3.82–6.23)

3.59 (2.39–5.39)

4.89 (3.66–6.53)

8.21 (5.18–13.0)

 P for trend

0.10

0.21

0.03

0.052

Liver fat content (mild vs. moderate and severe)

 HOMA-IR Q1

Reference

Reference

 HOMA-IR Q2

1.12 (0.48–3.35)

1.45 (0.12–17.2)

 HOMA-IR Q3

2.19 (0.94–5.11)

2.79 (0.33–24.0)

 HOMA-IR Q4

10.92 (4.59–25.9)

20.3 (2.49–30.1)

 P for trend

0.029

0.039