Rosiglitazone | Metformin | Rosiglitazone plus metformin | Insulin aspart 30 | |||||
---|---|---|---|---|---|---|---|---|
Baseline | 48 weeks | Baseline | 48 weeks | Baseline | 48 weeks | Baseline | 48 weeks | |
TNFα (pg/mL) | 28.57 ± 10.37 | 22.12 ± 11.66* | 30.24 ± 15.78 | 28.33 ± 12.34 | 27.91 ± 12.21 | 21.59 ± 9.82* | 28.75 ± 13.84 | 27.87 ± 10.22 |
IL-6 (pg/mL) | 8.13 ± 2.22 | 6.68 ± 3.69* | 9.21 ± 3.12 | 8.79.45 ± 4.01 | 8.88 ± 3.91 | 5.13 ± 3.93*a | 8.29 ± 4.63 | 7.31 ± 4.35 |
Il-1β (ng/mL) | 3.65 ± 1.63 | 3.71 ± 1.98 | 3.93 ± 2.95 | 3.52 ± 2.07 | 3.78 ± 2.26 | 4.02 ± 1.99 | 3.65 ± 2.62 | 4.83 ± 1.59 |
hs-CRP (mg/L) | 4.45 ± 1.51 | 3.24 ± 1.96* | 4.90 ± 1.98 | 3.01 ± 1.77* | 4.86 ± 1.70 | 2.23 ± 1.57*a | 4.67 ± 1.37 | 4.11 ± 1.18 |
SOD (kU/L) | 72.62 ± 18.56 | 76.36 ± 20.26* | 76.32 ± 20.21 | 80.55 ± 25.27△ | 74.98 ± 19.50 | 79.24 ± 23.70△a | 75.46 ± 21.56 | 78.68 ± 22.33△ |
MDA (μmol/L) | 6.03 ± 1.42 | 4.28 ± 1.94* | 6.94 ± 1.68 | 5.22 ± 1.73* | 6.53 ± 1.25 | 4.98 ± 1.56* | 6.14 ± 1.88 | 4.38 ± 1.62* |
8-iso-PGF2α (μg/L) | 10.35 ± 4.44 | 8.87 ± 5.91* | 12.11 ± 7.66 | 7.65 ± 7.15* | 11.30 ± 6.80 | 7.22 ± 6.31*a | 10.87 ± 6.83 | 8.94 ± 6.34* |
TAC (kU/L) | 24.62 ± 10.69 | 27.30 ± 12.35* | 25.31 ± 12.24 | 28.97 ± 9.18* | 23.66 ± 11.01 | 27.00 ± 10.82* | 24.48 ± 12.47 | 28.83 ± 10.82* |