Fig. 1
Biochemical and oxidative stress biomarkers of STZ-diabetic rats treated with curcumin alone or combined with metformin. Plasma levels of glucose (A), triacylglycerol (B), cholesterol (C), TBARS (D), fluorescent AGEs (E), and PON 1 activity (F). Values are expressed as mean ± SEM, n = 10. NYOG: normal rats treated with yoghurt; DYOG: diabetic rats treated with yoghurt; DINS: diabetic rats treated with 4 U/day insulin; DC90: diabetic rats treated with 90 mg/kg curcumin in yoghurt; DM250: diabetic rats treated with 250 mg/kg metformin in yoghurt; DC90M250: diabetic rats treated with 90 mg/kg curcumin + 250 mg/kg metformin in yoghurt. The differences between groups were considered significant at p < 0.05 and were analyzed using one-way ANOVA followed by Student–Newman–Keuls test. aDifferences with NYOG; bdifferences with DYOG; cdifferences with DINS; ddifferences with DC90; edifferences with DM250; fdifferences with DC90DM250