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Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: Serum concentration and vascular expression of adiponectin are differentially associated with the diabetic calcifying peripheral arteriopathy

Fig. 3

Immunohistochemical staining of adiponectin in arteries from patients with type 2 diabetes. Adiponectin (ADIPOQ) protein expression and localization was examined by immunohistochemistry staining in arteries from diabetic patients, classified according to the grade of calcification. ADIPOQ (red signal) was found to be expressed in all stages of calcification, but it was particularly enriched in early stages (grade 1). Smooth muscle cells of the media were specifically immuno positive for ADIPOQ, but the signal was also present in microvessels of the adventitia (particularly grade 2). Images were taken with ×5 magnification and enlarged images with ×15 (size bars included)

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