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Table 4 Linear multivariate analyses with changes in d-ROMs as dependent variables

From: Association of glucose and blood pressure variability on oxidative stress in patients with type 2 diabetes mellitus and hypertension: a cross-sectional study

  Dependent variables: d-ROMs (U.CARR)
β coefficient t value p value Full-model R2
Model 1    < 0.001** 0.396
 MAGE 0.311 2.831 0.006**  
 eGFR −0.228 −2.211 0.031*  
 Smoking 0.365 3.376 0.001**  
 Nighttime SD of DBP 0.225 2.036 0.047*  
Model 2    < 0.001** 0.439
 MAGE 0.321 3.147 0.003**  
 eGFR − 0.204 − 2.032 0.047*  
 Smoking 0.379 3.646 0.001**  
 Nighttime CV of DBP 0.258 2.484 0.016*  
  1. Multiple stepwise regression analysis, with d-ROMs as the dependent variable, adjusted for sex (female), age, duration of diabetes, body mass index, smoking status (current), use of insulin, glucose-like peptide-1 receptor agonists, dipeptidyl peptidase 4 inhibitors, sulfonylureas, glinides, α-glucosidase inhibitors, metformin, thiazolidine, sodium glucose cotransporter 2 inhibitors, statins, angiotensin II receptor blockers, calcium channel blockers, diuretics, α and β blockers, estimated glomerular filtration rate, FPG, MGL, HbA1c, %CV, MAGE, AUCPP, daytime AV of SBP, daytime SD of SBP, daytime AV of DBP, daytime SD of DBP, nighttime AV of SBP, nighttime SD of SBP, nighttime AV of DBP, nighttime SD of DBP, HDL-C, LDL-C, and TG
  2. d-ROMs diacron-reactive oxygen metabolites, FPG fasting plasma glucose state, MGL mean glucose level over 24 h, HbA1c hemoglobin A1c, MAGE mean amplitude of glycemic excursions, AUCPP total area under the postprandial plasma glucose curve, AV average, SD standard deviation, CV coefficient of variation, SBP systolic blood pressure, DBP diastolic blood pressure, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride
  3. *p < 0.05, **p < 0.01