Skip to main content

Advertisement

Table 1 Baseline clinical characteristics of subjects

From: Association of glucose and blood pressure variability on oxidative stress in patients with type 2 diabetes mellitus and hypertension: a cross-sectional study

Clinical characteristics Mean ± SD, n (%)
Age (years) 64.5 ± 13.3
Sex (male) 34 (56.7)
Body mass index (kg/m2) 27.6 ± 4.5
Smoking (%) 12 (20.0)
Drinking (%) 17 (28.3)
Duration of diabetes (years) 13.9 ± 12.4
Dyslipidemia 48 (80.0)
 Low-density lipoprotein cholesterol (mg/dL) 108.3 ± 36.4
 High-density lipoprotein cholesterol (mg/dL) 44.2 ± 12.0
 Triglycerides (mg/dL) 152.3 ± 74.1
Estimated glomerular filtration rate (mL/min/1.73 m2) 75.0 ± 21.3
HbA1c (%) 8.5 ± 1.2
Mean glucose level (mg/dL) 182.2 ± 36.7
Markers of glucose variability
 %CV 23.7 ± 5.7
 MAGE (mg/dL) 125.9 ± 35.2
Fasting plasma glucose state (mg/dL) 141.9 ± 33.9
AUCPP (mg/dL/h) 470.6 ± 291.1
Markers of BP variability
 Daytime average of SBP (mmHg) 129.9 ± 14.7
 Daytime SD of SBP (mmHg) 15.0 ± 4.5
 Daytime CV of SBP (mmHg) 11.6 ± 3.5
 Daytime average of DBP (mmHg) 76.6 ± 10.8
 Daytime SD of DBP (mmHg) 9.9 ± 3.1
 Daytime CV of DBP (mmHg) 13.0 ± 4.1
 Nighttime average of SBP (mmHg) 122.2 ± 17.8
 Nighttime SD of SBP (mmHg) 13.4 ± 3.9
 Nighttime CV of SBP (mmHg) 11.1 ± 3.3
 Nighttime average of DBP (mmHg) 70.9 ± 12.6
 Nighttime SD of DBP (mmHg) 8.3 ± 2.6
 Nighttime CV of DBP (mmHg) 12.0 ± 4.2
Dipper/non-dipper/riser/extreme-dipper 16/27/16/1
LF/HF ratio 3.7 ± 2.3
CVR–R (%) 2.9 ± 2.1
d-ROMs (U.CARR) 356.1 ± 66.7
Macroangiopathy 14 (23.3)
Nephropathy 25 (41.7)
Neuropathy 31 (51.7)
Retinopathy 21 (35.0)
Diabetes therapy
 Diet alone 16 (26.7)
 Metformin 21 (35.0)
 Sulfonylurea 24 (40.0)
 Glinide 0 (0.0)
 α-Glucosidase inhibitor 11 (18.3)
 Thiazolidine 11 (18.3)
 Dipeptidyl peptidase 4 inhibitor 25 (41.7)
 Sodium glucose cotransporter 2 inhibitors 6 (10.0)
 Glucose-like peptide 1 receptor agonist 7 (11.7)
 Insulin 14 (23.3)
Antihypertensive drugs
 Diet alone 23 (38.3)
 Angiotensin II receptor blocker 26 (43.3)
 Calcium channel blocker 29 (48.3)
 Diuretic 5 (8.3)
 α Blocker 1 (1.7)
 β Blocker 4 (6.7)
Other treatments
 Lipid-lowering drugs (statins) 33 (55.0)
  1. Data are mean ± SD, n (%)
  2. 1 U.CARR (arbitrary unit) = the oxidant capacity of a 0.08 mg/dL H2O2 solution
  3. HbA1c hemoglobin A1c, %CV percentage coefficient of variation for glucose, MAGE mean amplitude of glycemic excursions, AUCPP area under the postprandial plasma glucose curve, CV coefficient of variation, SD standard deviation, SBP systolic blood pressure, DBP diastolic blood pressure, LF/HF low frequency power/high-frequency power, CVR–R coefficient of variation in the R–R intervals, d-ROMs diacron-reactive oxygen metabolites