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Table 4 Investigation of the interactions between major dietary patterns and GC1F, GC1S and GC2 haplotypesc on the risk of MetS

From: Interactions between vitamin D binding protein variants and major dietary patterns on the odds of metabolic syndrome and its components in apparently healthy adults

MetS components

Dietary patterna

Healthy

Traditional

Western

TG

 Crude model

  P-interaction

0.20

0.69

0.51

  OR (%95CI)

0. 88 (0.73, 1.06)

1. 03 (0.86, 1.25)

1. 06 (0.87, 1.29)

 Adjusted modelb

  P-interaction

0.01

0.33

0.79

  OR (%95CI)

0. 72 (0.56, 0.93)

1.13 (0.71, 0.99)

1. 03 (0.78, 1.36)

HDL

 Crude model

  P-interaction

0.36

0.74

0.65

  OR (%95CI)

0. 92 (0.79, 1.09)

1.02 (0.87, 1.19)

1. 03 (0.87, 1.22)

 Adjusted model

  P-interaction

0.60

0.18

0.87

  OR (%95CI)

0. 95 (0.78, 1.15)

1. 14 (0.93, 1.39)

1. 01 (0.82, 1.26)

WC

 Crude model

  P-interaction

0.99

0.04

0.01

  OR (%95CI)

1. 00 (0.84, 1.78)

0. 84 (0.71, 0.99)

1. 25 (1.04, 1.21)

 Adjusted model

  P-interaction

0.99

0.003

0.70

  OR (%95CI)

0. 99 (0.80, 1.24)

0. 69 (0.55, 0.88)

1. 04 (0.81, 1.34)

FBS

 Crude model

  P-interaction

0.12

0.59

0.21

  OR (%95CI)

1. 39 (0.91, 2.12)

0. 88 (0.55, 1.40)

0. 74 (0.46, 1.18)

 Adjusted model

  P-interaction

0.04

0.11

0.11

  OR (%95CI)

0. 36 (0.14, 0.96)

0. 51 (0.22, 1.18)

0. 46 (0.18, 1.21)

BP

 Crude model

  P-interaction

0.09

0.16

0.95

  OR (%95CI)

0. 85 (0.70, 1.02)

1. 14 (0.94, 1.37)

0. 99 (0.81, 1.20)

 Adjusted model

  P-interaction

0.06

0.02

0.64

  OR (%95CI)

0. 79 (0.62, 1.01)

1. 31 (1.02, 1.68)

0. 94 (0.72, 1.22)

MetS

 Crude model

  P-interaction

0.12

0.91

0.16

  OR (%95CI)

0. 83 (0.85, 1.05)

0. 98 (0.78, 1.24)

1. 19 (0.93, 1.52)

 Adjusted model

  P-interaction

< 0.001

0.80

0.44

  OR (%95CI)

0. 64 (0.47, 0.87)

1. 03 (0.77, 1.40)

1. 13 (0.82, 1.57)

  1. Italic values indicate a significant difference (P ≤ 0.05)
  2. FBS fasting blood sugar, TG triglyceride, HDL high density lipoprotein, WC waist circumference, MetS metabolic syndrome, BP blood pressure
  3. a First quartile is used as reference (low adherence)
  4. b Adjusted for sex, age, physical activity and vitamin D
  5. c GC1F is used as reference (low risk)