Variables | NGT n = 263 | Prediabetes n = 161 | T2DM n = 85 | P | P trend |
---|---|---|---|---|---|
Age (years) | 59.4 ± 6.6 | 60.4 ± 7.4 | 62.7 ± 6.1a, b | 0.001 | < 0.001 |
BMI (kg/m2) | 22.2 ± 2.8 | 23.4 ± 2.9a | 23.7 ± 2.9a | < 0.001 | < 0.001 |
WHR | 0.89 ± 0.06 | 0.92 ± 0.10a | 0.93 ± 0.06a | < 0.001 | < 0.001 |
Female (n, %) | 143 (54.4) | 78 (48.4) | 52 (61.2) | 0.154 | 0.153 |
Education (n, %) | 0.135 | 0.124 | |||
Primary school and below | 157 (59.7) | 91 (56.5) | 62 (71.9) | ||
Middle school | 76 (28.9) | 53 (32.9) | 17 (20.0) | ||
High school and above | 30 (11.4) | 17 (10.6) | 6 (7.1) | ||
Smoking status (n, %) | 0.163 | 0.158 | |||
Non-smoker | 165 (62.7) | 93 (57.8) | 55 (64.7) | ||
Ever-smoker | 28 (10.7) | 29 (18.0) | 1 (16.5) | ||
Current-smoker | 70 (26.6) | 39 (24.2) | 16 (18.8) | ||
Drinking status (n, %) | 0.029 | 0.026 | |||
Non-drinker | 118 (44.9) | 66 (41.0) | 49 (57.7) | ||
Ever-drinker | 17 (6.4) | 4 (2.5) | 4 (4.7) | ||
Current-drinker | 128 (48.7) | 91 (56.5) | 32 (37.6) | ||
LDL-C (mmol/L) | 2.50 ± 0.67 | 2.73 ± 0.72a | 2.64 ± 0.76 | 0.003 | 0.015 |
HDL-C (mmol/L) | 1.34 ± 0.32 | 1.31 ± 0.33 | 1.34 ± 0.38 | 0.740 | 0.785 |
TG (mmol/L) | 1.42 ± 0.90 | 1.78 ± 1.14a | 2.01 ± 1.50a | < 0.001 | < 0.001 |
TC (mmol/L) | 4.77 ± 0.85 | 5.14 ± 0.94a | 5.20 ± 1.00a | < 0.001 | < 0.001 |
HbA1c (%) | 5.52 ± 0.34 | 5.65 ± 0.32 | 6.72 ± 0.71a, b | < 0.001 | < 0.001 |
FPG (mmol/L) | 5.24 ± 0.37 | 5.55 ± 0.49 | 7.43 ± 0.57a, b | < 0.001 | < 0.001 |
2 h-PG (mmol/L) | 6.26 ± 1.05 | 8.90 ± 1.20a | 13.92 ± 1.38a, b | < 0.001 | < 0.001 |
SBP (mmHg) | 120.6 ± 15.8 | 127.2 ± 13.2a | 130.7 ± 16.2a | < 0.001 | < 0.001 |
DBP (mmHg) | 71.1 ± 9.2 | 74.5 ± 7.9a | 75.4 ± 8.4a | < 0.001 | < 0.001 |
Adipo-IR | |||||
Q1 (≤ 1.52) | 92 (35.0) | 23 (14.3) | 11 (12.9) | < 0.001 | < 0.001 |
Q2 (1.53–2.37) | 68 (25.9) | 40 (24.8) | 13 (15.3) | ||
Q3 (2.38–3.70) | 68 (25.9) | 42 (26.1) | 20 (23.5) | ||
Q4 (≥ 3.71) | 35 (13.3) | 56 (34.8) | 41 (48.2) | ||
HOMA-IR | |||||
Q1 (≤ 0.87) | 82 (31.2) | 28 (17.4) | 11 (12.9) | < 0.001 | < 0.001 |
Q2 (0.88–1.29) | 76 (28.9) | 38 (23.6) | 8 (9.4) | ||
Q3 (1.30–1.91) | 66 (25.1) | 45 (28.0) | 23 (27.1) | ||
Q4 (≥ 1.92) | 39 (14.8) | 50 (31.0) | 43 (50.6) | ||
HOMA-β | |||||
Q1 (≤ 40.12) | 59 (22.4) | 36 (22.3) | 43 (50.6) | < 0.001 | 0.135 |
Q2 (40.13–56.04) | 76 (28.9) | 33 (20.5) | 17 (20.0) | ||
Q3 (56.05–80.23) | 69 (26.3) | 45 (28.0) | 10 (11.8) | ||
Q4 (≥ 80.24) | 59 (22.4) | 47 (29.2) | 15 (17.6) | ||
Fasting CPRI | |||||
Q1 (≤ 1.16) | 70 (26.6) | 30 (18.6) | 28 (32.9) | 0.005 | 0.005 |
Q2 (1.17–1.48) | 77 (29.3) | 32 (19.9) | 25 (29.4) | ||
Q3 (1.49–1.92) | 62 (23.6) | 48 (29.8) | 14 (16.5) | ||
Q4 (≥ 1.93) | 54 (20.5) | 51 (31.7) | 18 (21.2) | ||
Postprandial CPRI | |||||
Q1 (≤ 4.41) | 54 (20.5) | 31 (19.3) | 36 (42.4) | < 0.001 | < 0.001 |
Q2 (4.42–5.53) | 62 (23.6) | 48 (29.8) | 10 (11.8) | ||
Q3 (5.54–7.08) | 69 (26.2) | 44 (27.3) | 7 (8.3) | ||
Q4 (≥ 7.09) | 78 (29.7) | 38 (23.6) | 3 (3.5) |