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Table 2 Cox models for type 2 diabetes in relation to plasma albumin

From: Reduced plasma albumin predicts type 2 diabetes and is associated with greater adipose tissue macrophage content and activation

Model adjustments

HR

(95% CI)

p value

Unadjusted model

 Albumin

0.63

(0.51, 0.78)

< 0.0001

Adjusted model 1

 Albumin

0.71

(0.56, 0.90)

0.005

Adjusted model 2

 Albumin

0.77

(0.60, 0.97)

0.03

 Body fat percentage

1.49

(1.12, 1.98)

0.007

Adjusted model 3

 Albumin

0.74

(0.57, 0.95)

0.02

 Body fat percentage

1.22

(0.88, 1.69)

0.24

 M (log)

0.39

(0.28, 0.55)

< 0.0001

 AIR (log)

0.64

(0.53, 0.77)

< 0.0001

Adjusted model 4

 Albumin

0.75

(0.58, 0.96)

0.02

 Body fat percentage

1.26

(0.91, 1.77)

0.17

 M (log)

0.47

(0.32, 0.68)

< 0.0001

 AIR (log)

0.71

(0.53, 0.78)

0.0007

 FPG

0.99

(0.77, 1.28)

0.93

 2-h PG

1.38

(1.09, 1.75)

0.007

  1. Models 1–4 are also adjusted for age, sex and American Indian heritage
  2. Albumin, body fat percentage, M, AIR, and 2h-PG were standardized to a normal distribution with SD = 1
  3. AIR acute insulin response, FPG fasting plasma glucose, 2h-PG 2 h plasma glucose