Table 2 Cox regression analysis of significant main effects and interactions of total bilirubin and gamma-glutamyltransferase on incident metabolic syndrome
Predictor variables | Men and women | Men | Women | |||
|---|---|---|---|---|---|---|
Hazard ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | |
Main effects | ||||||
 Total bilirubin (low total bilirubin) | ||||||
  High total bilirubin | 0.70 (0.59–0.85) | 0.0001 | 0.82 (0.66–1.01) | 0.0677 | 0.60 (0.43–0.84) | 0.0022 |
 Gamma-glutamyltransferase (low gamma-glutamyltransferase) | ||||||
  High gamma-glutamyltransferase | 3.21 (2.69–3.87) | < 0.0001 | 2.99 (2.42–3.73) | < 0.0001 | 3.67 (2.66–5.20) | < 0.0001 |
Interaction effects | ||||||
 Total bilirubin × gamma-glutamyltransferase |  | 0.0222 |  | 0.0764 |  | 0.0857 |