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Fig. 1 | Diabetology & Metabolic Syndrome

Fig. 1

From: 1α,25(OH)2D3 attenuates IL-6 and IL-1β-mediated inflammatory responses in macrophage conditioned medium-stimulated human white preadipocytes by modulating p44/42 MAPK and NF-κB signaling pathways

Fig. 1

Effects of MacCM on cytokine release from human white preadipocytes. Preadipocytes were either cultured alone (control), or with THP-1-MacCM (25%) for 24 h before supernatant collection. a Secreted cytokines were screened by cytokine array. b The results are presented as pixel density relative to the reference controls of the arrays. The concentrations of pro-inflammatory factors c IL-1β, d IL-6, e IL-8, f MCP-1 and g RANTES were also measured by ELISA. Data are shown as mean ± SEM for groups of 6. The results were analyzed using unpaired Student’s t test and confirmed by three independent experiments. A significant difference to control was indicated by ***(p < 0.001)

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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