From: Leptin-deficient mice have altered three-dimensional growth plate histomorphometry
Lean (+/+) | Obese (ob/ob) | P | |
---|---|---|---|
Body mass at 5 weeks (g) | 21.7 ± 0.64 | 22.1 ± 0.85 | 0.01 |
Body mass at 10 weeks (g) | 23.4 ± 0.34 | 24.8 ± 0.95 | 0.01 |
Tibia length (mm) | 17.9 ± 0.11 | 17.2 ± 0.61 | 0.02 |
Growth plate height (mm) | 1.58 ± 0.12 | 0.84 ± 0.22 | 0.01 |
Chondrocyte column count | 53.9 ± 8.2 | 43.6 ± 2.7 | 0.02 |