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Table 2 Results of weight and laboratory parameters of C-Reactive Protein, tumor necrosis factor alpha, and glycosylated hemoglobin measured before and 8 weeks after treatment with exenatide in a subcohort of 56 patients with type 2 diabetes mellitus, subdivided according to TCF7L2 genotype

From: Effect of TCF7L2 polymorphism on pancreatic hormones after exenatide in type 2 diabetes

Variable Comparison Standard error p IC (95%)
Inferior Superior
Weight (kg) CC (pre) VS CC (post) 0.04 < 0.001 2.08 2.25
CC (pre) VS CT/TT (pre) 3.71 NS − 7.51 7.05
CC (post) VS CT/TT (post) 3.71 NS − 7.19 7.37
CT/TT (pre) VS CT/TT (post) 0.04 < 0.001 2.41 2.56
HbA1C (%) Pre × post 0.11 0.036 0.02 0.46
CRP (mg/dL) CC (pre) × CC (post) 0.33 NS − 1.02 0.27
CC (pre) × CT/TT (pre) 1.27 NS − 4.18 0.81
CC (post) × CT/TT (post) 1.15 NS − 2.52 1.99
CT/TT(pre) × CT/TT(post) 0.46 NS 0.15 1.94
TNFα (pg/mL) CC × CT/TT 0.12 < 0.001 − 0.96 − 0.48
Pre × post 0.04 < 0.001 0.23 0.41
  1. Italic values indicate statistically significant associations
  2. pre before treatment, post after treatment, NS non-significant