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Table 3 Multivariate analysis of cancer mortality with metabolic syndrome by sex

From: Metabolic syndrome is a risk factor for cancer mortality in the general Japanese population: the Jichi Medical School Cohort Study

 

Men

Women

Without MetS

With MetS

Without MetS

With MetS

MetS participants, n (%)

3973 (88.4)

522 (11.6)

6406 (91.1)

622 (8.9)

Cancer deaths

418

55

251

46

Parson-Years

71,444

9418

120,718

11,654

Cancer mortality

 Crude mortality (/1000 person-years)

5.9

5.8

2.1

3.9

 HR-Agea (95% CI)

1.0 (reference)

1.11 (0.84–1.48)

1.0 (reference)

1.69 (1.23–2.31)

 HR-Allb (95% CI)

1.0 (reference)

1.21 (0.90–1.62)

1.0 (reference)

1.69 (1.21–2.36)

< 65 years old

 Crude mortality (/1000 person-years)

3.3

3.8

1.3

2.4

 HR-Agea (95% CI)

1.0 (reference)

1.14 (0.80–1.61)

1.0 (reference)

1.70 (1.14–2.55)

 HR-Allb (95% CI)

1.0 (reference)

1.22 (0.84–1.77)

1.0 (reference)

1.66 (1.09–2.55)

≥ 65 years old

 Crude mortality (/1000 person-years)

2.6

2.0

0.8

1.5

 HR-Agea (95% CI)

1.0 (reference)

1.09 (0.68–1.74)

1.0 (reference)

1.71 (1.03–2.83)

 HR-Allb (95% CI)

1.0 (reference)

1.19 (0.73–1.95)

1.0 (reference)

1.69 (0.99–2.89)

  1. MetS metabolic syndrome, HR hazard ratio, CI confidence interval
  2. aHazard ratios adjusted for age
  3. bHazard ratios adjusted for age, smoking status (never, past, or current smoker), alcohol drinking status (never, past, or current drinker), marital status (yes or no), educational attainment (≤ 15, 16–18, or ≥ 19 years), physical activity (low, middle, high), occupation category (white-collar, blue-collar, or no working), and menopausal status (pre or post) only in women