| Participants | Cancer deaths | Person-years | Crude mortality (/1000 person-years) | Total HR-ageb (95% CI) | Total HR-allc (95% CI) | Men HR-allc (95% CI) | Women HR-allc (95% CI) |
---|---|---|---|---|---|---|---|---|
No. of metabolic risk factorsa | ||||||||
 0 | 3439 | 173 | 64,584 | 2.7 | 1.00 | 1.00 | 1.00 | 1.00 |
 1 | 4111 | 269 | 75,684 | 3.6 | 1.02 (0.84–1.24) | 0.92 (0.76–1.12) | 0.95 (0.73–1.23) | 0.88 (0.64–1.20) |
 2 | 2628 | 212 | 48,329 | 4.4 | 1.17 (0.95–1.43) | 1.10 (0.89–1.36) | 1.14 (0.87–1.49) | 1.04 (0.74–1.46) |
 3 | 1149 | 90 | 21,050 | 4.3 | 1.23 (0.95–1.59) | 1.19 (0.92–1.55) | 1.08 (0.76–1.54) | 1.37 (0.92–2.05) |
 4 | 196 | 26 | 3512 | 7.4 | 2.14 (1.41–3.23) | 1.91 (1.23–2.96) | 1.68 (0.95–2.95) | 2.32 (1.16–4.66) |
P for trend | Â | Â | Â | Â | 0.002 | 0.007 | 0.103 | 0.027 |
Combination of obesity and 3 other risk factors | Â | Â | Â | Â | Â | Â | Â | Â |
 Non-obesity and 0–1 risk factors | 7077 | 422 | 131,208 | 3.2 | 1.00 | 1.00 | 1.00 | 1.00 |
 Non-obesity and 2 risk factors | 1451 | 136 | 26,162 | 5.2 | 1.25 (1.03–1.52) | 1.18 (0.97–1.45) | 1.28 (1.02–1.62) | 0.89 (0.60–1.34) |
 Non-obesity and 3 risk factors | 201 | 15 | 3499 | 4.3 | 1.04 (0.62–1.74) | 0.98 (0.57–1.67) | 0.99 (0.53–1.88) | 0.90 (0.34–2.45) |
 Obesity and 0–1 risk factors | 1650 | 96 | 31,268 | 3.1 | 0.93 (0.74–1.16) | 1.04 (0.82–1.32) | 0.85 (0.58–1.22) | 1.28 (0.93–1.76) |
 Obesity and 2 risk factors | 948 | 75 | 17,560 | 4.3 | 1.24 (0.97–1.59) | 1.32 (1.02–1.71) | 1.14 (0.80–1.61) | 1.61 (1.10–2.36) |
 Obesity and 3 risk factors | 196 | 26 | 3512 | 7.4 | 2.08 (1.40–3.10) | 1.99 (1.31–3.04) | 1.71 (0.99–2.95) | 2.50 (1.27–4.92) |