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Table 2 Anthropometric, fat mass ratio and biochemical characteristics of patients with a clinical diagnosis of FPL syndrome

From: Evaluation of the hypothalamic–pituitary–adrenal axis in a case series of familial partial lipodystrophy

  P1 P2 P3 P4 P5 P6
BMI (kg/m2) 22.5 31.7 27.7 39.5 27.9 41.9
WC (cm) 78 96 93 122 92 110
WHR 0.92 0.92 1.02 1.07 1.0 1.02
BAI (%) 22.6 25.8 27.0 34.6 32.4 39.4
FMR 1.70 1.56 1.64 1.35 1.84 1.29
Glucose (mg/dL) 78 72 95a 107 142a 89
Insulin (mcUi/mL) 132.9 19.4 34.3 190.6 159.3 25.4
HOMA-IR 25.57 3.45 16.5 47.6 55.8 5.64
HbA1c (%) 5.8 5.8 8.9 5.8 7.6 5.5
Leptin (ng/mL) 4.1 2.8 3.7 55 17 76
ALT (U/L) 22 21 66 96 33 18
HDL (mg/dL) 26 30 21 45 22 55
Triglycerides (mg/dL) 582 163 500b 258 287c 152
  1. BMI body mass index, WC waist circumference, WHR waist-to-hip ratio, BAI body adiposity index, FMR % truncal fat/lower limbs fat, HOMA-IR homeostatic model assessment of insulin resistance, ALT aspartate aminotransferase
  2. aUse of the anti-diabetic medications gliclazide and metformin
  3. bUse of fibrate
  4. cUse of statin, fibrate and ezetimibe