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Table 2 Anthropometric, fat mass ratio and biochemical characteristics of patients with a clinical diagnosis of FPL syndrome

From: Evaluation of the hypothalamic–pituitary–adrenal axis in a case series of familial partial lipodystrophy

 

P1

P2

P3

P4

P5

P6

BMI (kg/m2)

22.5

31.7

27.7

39.5

27.9

41.9

WC (cm)

78

96

93

122

92

110

WHR

0.92

0.92

1.02

1.07

1.0

1.02

BAI (%)

22.6

25.8

27.0

34.6

32.4

39.4

FMR

1.70

1.56

1.64

1.35

1.84

1.29

Glucose (mg/dL)

78

72

95a

107

142a

89

Insulin (mcUi/mL)

132.9

19.4

34.3

190.6

159.3

25.4

HOMA-IR

25.57

3.45

16.5

47.6

55.8

5.64

HbA1c (%)

5.8

5.8

8.9

5.8

7.6

5.5

Leptin (ng/mL)

4.1

2.8

3.7

55

17

76

ALT (U/L)

22

21

66

96

33

18

HDL (mg/dL)

26

30

21

45

22

55

Triglycerides (mg/dL)

582

163

500b

258

287c

152

  1. BMI body mass index, WC waist circumference, WHR waist-to-hip ratio, BAI body adiposity index, FMR % truncal fat/lower limbs fat, HOMA-IR homeostatic model assessment of insulin resistance, ALT aspartate aminotransferase
  2. aUse of the anti-diabetic medications gliclazide and metformin
  3. bUse of fibrate
  4. cUse of statin, fibrate and ezetimibe