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Table 3 Comparisons the levels of 8-OH-dG, 8-iso-PGF2α and hsCRP before and after 8-week treatment between two groups

From: Liraglutide ameliorates beta-cell function, alleviates oxidative stress and inhibits low grade inflammation in young patients with new-onset type 2 diabetes

Variable

Liraglutide group

Metformin group

Pre-treatment

Post-treatment

P-value

Pre-treatment

Post-treatment

P-value

8-OH-dG (ng/mL)

35.95

(29.30, 50.70)

18.74

(4.84, 24.20)

0.002

16.77

(9.71, 32.60)

7.86

(2.87, 23.31)

0.027

8-iso-PGF2α (ng/mL)

1345

(885, 1920)

288

(183, 472)

0.001

1180

(1025, 1765)

299

(228, 586)

0.001

hsCRP (mg/L)

1.96

(1.11, 3.89)

1.47

(0.53, 1.86)

0.002

1.88

(1.06, 3.69)

1.44

(0.67, 2.35)

0.017

  1. Data are expressed as median (interquartile rang)
  2. 8-OH-dG, 8-hydroxy-2′-deoxyguanosine; 8-iso-PGF2α, 8-isoprostane F2α; hsCRP, high sensitivity C-reactive protein