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Table 2 Effect of lactoferrin on the serum levels of SOD, IL-1β, -6, -18 and lipocalin in type 2 diabetic patients

From: Antidiabetic efficacy of lactoferrin in type 2 diabetic pediatrics; controlling impact on PPAR-γ, SIRT-1, and TLR4 downstream signaling pathway

Variables

Diabetic patients (N = 30)

Controls (N = 30)

Before lactoferrin

After lactoferrin

SOD (U/mL)

143.6 ± 9.344a

175.9 ± 10.3b

222.5 ± 14.9

Interleukin-1β (pg/mL)

13.8 ± 1.8a

10.45 ± 1.37b

3.4 ± 0.8

Interleukin-6 (pg/mL)

16.78 ± 2a

11.5 ± 1.89b

4.9 ± 1.0

Interleukin-18 (pg/mL)

46.9 ± 6.4a

30.67 ± 4.15b

15.5 ± 2.87

Lipocalin 2 (pg/mL)

102.2 ± 11.7a

66.36 ± 13.2b

25.6 ± 3.9

  1. Values are means ± SDM
  2. SOD superoxide dismutase, IL interleukin
  3. aSignificant difference from normal group, at P ≤ 0.05
  4. bSignificant difference from diabetic patients before therapy, at P ≤ 0.05