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Table 1 Clinical and biochemical characteristics of the study population

From: LIPC variants as genetic determinants of adiposity status, visceral adiposity indicators, and triglyceride-glucose (TyG) index-related parameters mediated by serum triglyceride levels

  Total Men Women P value
Number 592 310 282  
Age (years) 45.8 ± 9.7 45.0 ± 9.6 46.7 ± 9.7 0.035
BMI (kg/m2) 24.3 ± 3.5 24.9 ± 3.2 23.6 ± 3.7 2.97 × 10−7
Waist circumference (cm) 85.0 ± 9.6 87.9 ± 7.8 81.8 ± 10.5 1.05 × 10−16
Current smokers (number; %) 115; 19.4 104; 33.5 11; 3.9 4.02 × 10−21
Systolic blood pressurea (mmHg) 113.1 ± 16.1 114.0 ± 14.3 112.1 ± 17.8 0.076
Diastolic blood pressurea (mmHg) 75.0 ± 9.9 76.8 ± 9.7 73.1 ± 9.9 6.9 × 10−6
HDL-C (mg/dL) 55.4 ± 14.3 49.9 ± 12.0 61.5 ± 14.2 2.16 × 10−25
TG (mg/dL) 142.5 ± 119.1 172.9 ± 148.0 109.2 ± 60.1 2.26 × 10−15
Fasting plasma glucose (mg/dL) 96.2 ± 22.6 99.0 ± 26.0 93.2 ± 17.8 5.40 × 10−5
Fasting serum insulin (µU/mL) 9.2 ± 4.9 9.8 ± 5.6 8.6 ± 3.9 0.005
HOMA-IR 2.2 ± 1.4 2.4 ± 1.6 2.0 ± 1.1 1.09 × 10−4
LAP 3560.2 ± 3902.0 4240.1 ± 4780.9 2812.8 ± 2412.0 1.30 × 10−7
VAI 196.1 ± 245.0 265.9 ± 308.9 119.4 ± 100.4 8.78 × 10−29
TyG index 8.6 ± 0.6 8.8 ± 0.7 8.4 ± 0.5 2.26 × 10−15
TyG-BMI 210.3 ± 38.3 220.5 ± 35.4 199.0 ± 38.2 1.24 × 10−13
TyG-WC 735.7 ± 116.8 777.3 ± 102.8 690.0 ± 114.3 6.27 × 10−23
  1. Continuous variables are presented as mean ± SD. HDL-C, TG, LAP, VAI, TyG, TyG-BMI and TyG-WC values were logarithmically transformed before statistical testing to meet the assumption of normal distributions; however, the untransformed data are shown
  2. BMI body mass index, HDL-C high-density lipoprotein cholesterol, TG triglycerides, HOMA-IR homeostasis model assessment of insulin resistance, LAP lipid accumulation product, VAI visceral adiposity index, TyG index the product of triglycerides and fasting glucose, WC waist circumference
  3. aOnly those participants not using antihypertensive drugs were analyzed