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Table 2 Logistic regression analysis—variables associated with achieving glycemic goals (individually adjusted A1c) during the last 2 years of insulin therapy follow up (Group 1)

From: Clinical inertia on insulin treatment intensification in type 2 diabetes mellitus patients of a tertiary public diabetes center with limited pharmacologic armamentarium from an upper-middle income country

Variable

Diabetes control

Total

ORCrude

95% CI

p

ORAdjusted

95% CI

p

No

Yes

Lower

Upper

Lower

Upper

Age, years

1.06

1.03

1.08

< 0.001

1.04

1.01

1.07

0.004

 Mean (sd)

64 (9.9)

69 (9.4)

65.8 (10)

        

 Median (min.; max.)

65 (37; 96)

70 (38; 92)

66 (37; 96)

        

Gender, n (%)

        

 Female

134 (68.7)

61 (31.3)

195

1.00

   

1.00

   

 Male

72 (56.7)

55 (43.3)

127

1.68

1.06

2.67

0.029

1.74

1.03

2.94

0.040

Duration of diabetes, years

1.00

0.97

1.03

0.899

    

 Mean (sd)

18.6 (7.5)

18.7 (7.6)

18.6 (7.5)

        

 Median (min.; max.)

17 (4; 42)

17 (4; 41)

17 (4; 42)

        

Duration of insulin use, years

0.97

0.91

1.03

0.294

    

 Mean (sd)

11.1 (6.7)

9.7 (6.3)

10.6 (6.6)

        

 Median (min.; max.)

10 (1; 29)

9 (1; 29)

10 (1; 29)

        

Systemic arterial hypertension, n (%)

        

 No

8 (66.7)

4 (33.3)

12

1.00

       

 Yes

198 (64.1)

111 (35.9)

309

1.12

0.33

3.81

0.854

    

Dyslipidemia, n (%)

        

 No

22 (61.1)

14 (38.9)

36

1.00

       

 Yes

183 (64.2)

102 (35.8)

285

0.88

0.43

1.79

0.715

    

Neuropathy, n (%)

        

 No

168 (65.4)

89 (34.6)

257

1.00

       

 Yes

33 (58.9)

23 (41.1)

56

1.32

0.73

2.38

0.363

    

Nephropathy, n (%)

        

 No

175 (67.8)

83 (32.2)

258

1.00

       

 Yes

24 (46.2)

28 (53.8)

52

2.46

1.34

4.50

0.004

    

Retinopathy, n (%)

        

 No

119 (69.6)

52 (30.4)

171

1.00

   

1.00

   

 Yes

81 (57.4)

60 (42.6)

141

1.70

1.06

2.70

0.027

1.65

0.98

2.78

0.060

Macroangiopathy, n (%)

        

 No

124 (70.9)

51 (29.1)

175

1.00

       

 Yes

77 (55.8)

61 (44.2)

138

1.93

1.21

3.08

0.006

    

Insulin daily dose, units/kg of body weight

0.51

0.26

1.01

0.052

    

 Mean (sd)

0.68 (0.43)

0.58 (0.33)

0.65 (0.4)

        

 Median (min.; max.)

0.61 (0.11; 3.33)

0.5 (0.07; 1.48)

0.58 (0.07; 3.33)

        

Glucose self monitoring daily

        

 No

70 (64.2)

39 (35.8)

109

1.00

       

 Yes

123 (64.4)

68 (35.6)

191

0.99

0.61

1.62

0.975

    
  1. Logistic regression
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Diabetology & Metabolic Syndrome

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