Table 4 Clinical characteristics of monkeys with USS0–1 or USS2–3
From: Characterization of spontaneously-developed non-alcoholic fatty liver disease in aged rhesus monkeys
Factor | All (n = 86) | USS 2–3 (n = 25) | USS 0–1 (n = 61) | p-value |
|---|---|---|---|---|
Age (years) | 18.1 ± 0.6 | 17.8 ± 0.5 | 18.2 ± 0.8 | 0.76 |
SBP (mmHg) | 127.1 ± 2.3 | 134.3 ± 4.3 | 124.1 ± 2.6 | 0.04 |
DBP (mmHg) | 76.4 ± 1.1 | 78.9 ± 1.9 | 75.4 ± 1.4 | 0.17 |
BW (kg) | 12.8 ± 0.5 | 16.7 ± 1.0 | 11.2 ± 0.4 | < 0.001 |
BMI | 17.9 ± 0.7 | 23.5 ± 1.4 | 15.6 ± 0.5 | < 0.001 |
WC (cm) | 45.0 ± 1.5 | 56.6 ± 3.0 | 40.2 ± 1.3 | < 0.001 |
FPG (mmol/L) | 4.6 ± 0.2 | 5.2 ± 0.6 | 4.3 ± 0.1 | 0.03 |
HOMA IR | 6.9 ± 1.6 | 14.3 ± 5.1 | 3.9 ± 0.5 | 0.003 |
Insulin (μU/ml) | 28.0 ± 3.9 | 50.1 ± 11.3 | 19.0 ± 2.1 | < 0.001 |
CRP (mg/dL) | 0.3 ± 0.1 | 0.4 ± 0.1 | 0.3 ± 0.1 | 0.26 |
TG (mmol/L) | 0.8 ± 0.1 | 1.3 ± 0.4 | 0.6 ± 0.0 | 0.005 |
TC (mmol/L) | 4.1 ± 0.2 | 4.9 ± 0.6 | 3.8 ± 0.2 | 0.03 |
HDL-c (mmol/L) | 1.9 ± 0.1 | 1.6 ± 0.1 | 2.0 ± 0.1 | 0.01 |
LDL-c (mmol/L) | 2.0 ± 0.2 | 2.9 ± 0.6 | 1.7 ± 0.2 | 0.01 |
NEFA (mmol/L) | 1.1 ± 0.1 | 1.4 ± 0.3 | 1.0 ± 0.1 | 0.10 |
ALT (U/L) | 61.7 ± 4.0 | 65.1 ± 8.2 | 60.3 ± 4.5 | 0.59 |
AST (U/L) | 27.4 ± 0.8 | 26.5 ± 1. | 27.7 ± 0.9 | 0.52 |