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Table 4 Baseline predictors at multivariate analysis for 4-year eGFR reduction > 30%

From: Normoalbuminuric kidney impairment in patients with T1DM: insights from annals initiative

 

Odds ratio

P

Odds ratio

P

Male sex

0.95 (0.55–1.65)

0.861

0.87 (0.49–1.53)

0.620

Age (by 10 years)

0.90 (0.73–1.11)

0.331

0.95 (0.76–1.18)

0.615

eGFR (by 10 mL/min/1.73 m2)

0.86 (0.70–1.06)

0.164

0.89 (0.72–1.11)

0.303

Albuminuria

4.09 (2.22–7.56)

< 0.001

 

Microalbuminuria

 

2.50 (1.26–4.95)

0.009

Macroalbuminuria

 

9.25 (4.44–19.25)

< 0.001

HbA1c (by 1%)

1.10 (0.92–1.31)

0.299

1.06 (0.88–1.27)

0.559

Triglycerides (by 10 mg/dL)

1.02 (0.99–1.05)

0.237

1.02 (0.99–1.06)

0.248

Systolic blood pressure (by 10 mmHg)

1.11 (0.97–1.27)

0.145

1.09 (0.95–1.25)

0.232

Proliferative retinopathy

2.39 (1.22–4.68)

0.011

2.36 (1.18–4.73)

0.016

Antihypertensive treatment

2.19 (0.97–4.92)

0.059

2.14 (0.93–4.92)

0.074

  1. Complete case analysis performed by using a logistic regression model including 427 patients (91 with eGFR reduction > 30%) for which all data were observed
  2. eGFR estimated glomerular filtration rate, HbA1c glycated haemoglobin