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Table 1 Systemic characteristics in the experimental pig groups (n = 5 each) at 16 weeks

From: The metabolic syndrome modifies the mRNA expression profile of extracellular vesicles derived from porcine mesenchymal stem cells

Parameter

Lean

MetS

p value

Body weight (kg)

69.3 ± 11.4

92.2 ± 4.4*

0.0005

Mean blood pressure (mmHg)

97.9 ± 13.1

124.1 ± 5.7*

0.002

Total cholesterol (mg/dL)

79.5 ± 7.3

354.2 ± 30.5*

< 0.0001

LDL cholesterol (mg/dL)

31.7 ± 6.9

349.0 ± 132.1*

0.0003

Triglycerides (mg/dL)

6.8 ± 1.7

17.1 ± 2.4*

0.0002

Fasting glucose (mg/dL)

108.8 ± 23.1

123.7 ± 22.3

0.207

Fasting insulin (µU/mL)

0.4 ± 0.1

0.7 ± 0.1*

0.002

HOMA-IR score

0.6 ± 0.1

1.7 ± 0.3*

< 0.0001

  1. HOMA homeostasis model assessment of insulin resistance, LDL low-density lipoprotein, Mets metabolic syndrome
  2. * p ≤ 0.05 vs. Lean