Optimal cut-off points for waist circumference in the definition of metabolic syndrome in Brazilian adults: baseline analyses of the Longitudinal Study of Adult Health (ELSA-Brasil)

Table 2 Cut-off points for waist circumference (WC) in the definition of metabolic syndrome as recommended by the Joint Interim Statement criteria (not including WC)

WC	Sens. %	Spec.%	PPV %	NPV %	Youden	Prevalence MetS^c (%)	Odds ratio^d
WC	Sens. %	Spec.%	PPV %	NPV %	Youden	Prevalence MetS^c (%)	Value	95% CI
Men
90^a	77.9	53.3	74.9	57.4	0.3119	54.1	1.26	1.22–1.30
91	74.8	57.6	76.0	56.0	0.3241	52.9	1.38	1.32–1.44
92	71.2	61.2	76.7	54.3	0.3245	51.5	1.50	1.42–1.59
93	67.7	64.5	77.4	52.7	0.3220	50.1	1.64	1.53–1.76
94^b	63.9	67.2	77.7	50.9	0.3110	48.6	1.78	1.64–1.93
95	59.7	70.8	78.5	49.5	0.3048	47.0	1.93	1.76–2.12
96	56.0	73.6	79.1	48.3	0.2954	45.7	2.09	1.88–2.32
97	52.2	76.6	80.0	47.2	0.2884	44.3	2.25	2.01–2.52
98	48.4	80.0	81.2	46.4	0.2836	43.0	2.42	2.14–2.73
99	44.8	82.8	82.3	45.5	0.2755	41.8	2.59	2.27–2.94
100	40.9	85.0	83.0	44.5	0.2593	40.4	2.76	2.41–3.15
101	37.9	86.5	83.4	43.8	0.2444	39.6	2.93	2.56–3.35
102	34.3	88.1	83.8	42.8	0.2244	38.4	3.10	2.71–3.55
Women
80^ab	87.4	41.9	55.3	80.2	0.2932	40.5	1.11	1.09–1.12
81	84.8	46.4	56.5	78.8	0.3122	39.8	1.22	1.19–1.25
82	82.4	50.3	57.6	77.6	0.3265	39.0	1.34	1.30–1.39
83	79.4	53.9	58.6	76.0	0.3322	38.1	1.48	1.42–1.54
84	77.2	57.6	59.9	75.5	0.3478	37.6	1.62	1.55–1.70
85	74.3	61.4	61.3	74.4	0.3574	36.6	1.77	1.68–1.87
86	70.8	65.1	62.5	73.0	0.3589	35.6	1.93	1.83–2.05
87	67.5	68.2	63.5	71.8	0.3566	34.7	2.10	1.98–2.24
88	64.1	71.1	64.5	70.6	0.3513	33.7	2.28	2.14–2.44
89	60.5	73.6	65.4	69.4	0.3419	32.6	2.47	2.30–2.66
90	57.1	76.2	66.4	68.4	0.3333	31.6	2.67	2.47–2.89

Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), 2008–2010
WC waist circumference, Sens. sensitivity, Spec. specificity, PPV positive predictive value, NPV negative predictive value, MetS metabolic syndrome, 95% CI 95% confidence interval
^a Cut-off suggested by the Joint Interim Statement (JIS) for Central and South Americans ethnic groups
^b Cut-off suggested by the JIS for white Caucasians/Europids or black Sub-Saharan African origin
^c Prevalence in the overall sex-specific sample
^d Relative odds of the metabolic syndrome being present above the cut-off point, reference strata being the lowest 25% of WCs

ISSN: 1758-5996