|
Clinical characteristics
|
Leptin (ng/ml)
|
Resistin (ng/ml)
|
Visfatin (ng/ml)
|
MCP-1 (pg/ml)
|
SFRP5 (ng/ml)
|
RBP4 (ng/ml)
|
|---|
|
ρ (rho)
|
P value
|
ρ (rho)
|
P value
|
ρ (rho)
|
P value
|
ρ (rho)
|
P value
|
ρ (rho)
|
P value
|
ρ (rho)
|
P value
|
|---|
|
Fasting glucose (mmol/l)
|
− 0.035
|
0.57
|
− 0.32
|
< 0.0001
|
− 0.22
|
0.006
|
− 0.42
|
< 0.0001
|
− 0.25
|
0.001
|
0.4
|
< 0.0001
|
|
Triglycerides (mmol/l)
|
0.13
|
0.043
|
− 0.13
|
0.048
|
0.12
|
0.15
|
− 0.02
|
0.75
|
− 0.05
|
0.54
|
0.16
|
0.038
|
|
Total cholesterol (mmol/l)
|
0.17
|
0.006
|
0.014
|
0.84
|
0.1
|
0.2
|
0.005
|
0.94
|
0.14
|
0.092
|
− 0.02
|
0.76
|
|
HDL-C (mmol/l)
|
− 0.007
|
0.91
|
0.082
|
0.21
|
− 0.03
|
0.71
|
0.065
|
0.3
|
0.051
|
0.53
|
− 0.16
|
0.015
|
|
LDL-C (mmol/l)
|
0.15
|
0.02
|
0.095
|
0.15
|
− 0.002
|
0.98
|
− 0.02
|
0.76
|
0.28
|
< 0.0001
|
− 0.04
|
0.57
|
|
Glycosylated hemoglobin (HbA1c) (%)
|
0.03
|
0.64
|
− 0.29
|
< 0.0001
|
− 0.17
|
0.34
|
− 0.35
|
< 0.0001
|
− 0.18
|
0.023
|
0.41
|
< 0.0001
|
|
Insulin (mIU/l)
|
0.43
|
< 0.0001
|
0.05
|
0.47
|
− 0.03
|
0.68
|
− 0.02
|
0.71
|
− 0.03
|
0.73
|
− 0.07
|
0.29
|
|
HOMA-IR
|
0.31
|
< 0.0001
|
− 0.14
|
0.34
|
− 0.15
|
0.064
|
− 0.25
|
< 0.0001
|
− 0.17
|
0.031
|
0.14
|
0.029
|
|
QUICKI
|
− 0.29
|
< 0.0001
|
0.13
|
0.057
|
0.17
|
0.038
|
0.26
|
< 0.0001
|
0.19
|
0.019
|
− 0.14
|
0.029
|
|
HOMA-β
|
0.3
|
< 0.0001
|
0.33
|
< 0.0001
|
0.14
|
0.084
|
0.33
|
< 0.0001
|
0.21
|
0.007
|
− 0.37
|
< 0.0001
|
- The correlations between studied adipokines and clinical parameters of overweight and T2DM were calculated by using Spearman’s rank correlation coefficient. Spearman’s rho (ρ) and P values are presented
- HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, HOMA-IR Homeostasis Model Assessment-Insulin Resistance, QUICKI Quantitative Insulin Sensitivity Check Index, HOMA-β homeostatic model assessment-β-cell function
