Fig. 3

Diagnostic performance of adipose tissue-derived cytokines and their relative ratios in insulin resistance/sensitivity and β-cell function. ROC curves of adipose tissue-derived cytokines and their relative ratios based on insulin resistance/sensitivity and β-cell function. HOMA-IR, QUICKI, and HOMA-β were used as the predictor variables and the cut-off values were defined as 25% percentile, median and 75% percentile of the control group. Different cut-off values were used to analyze and the best diagnostic performance was presented. a diagnostic performances of resistin/RBP4 ratio, resistin and RBP4 in β-cell function with HOMA-β of 65.6 (25% percentile) as cut-off value. b diagnostic performances of MCP-1/RBP4 ratio, MCP-1 and RBP4 in β-cell function with HOMA-β of 65.6 (25% percentile) as cut-off value. Diagnostic performances of Leptin/MCP-1, Leptin and MCP-1 in insulin resistance/sensitivity with HOMA-IR of 1.99 (median) as cut-off value (c) and QUICKI of 0.93 (median) as cut-off value (d)