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Table 5 Evaluation of the PM definition of the metabolic syndrome and individual criteria

From: Establishing post mortem criteria for the metabolic syndrome: an autopsy based cross-sectional study

 

Sensitivity (male/female)

Specificity (male/female)

Likelihood ratio (95% CI)

Difference PM vs. AM (95% CI)

P value

PM definition MetS

0.63 (0.70/0.57)

0.93 (0.94/0.91)

9.27 (6.05; 14.19)

2.3% (− 0.7%; 5.2%)

0.175

PM cholesterol

0.29 (0.38/0.17)

0.98 (0.98/0.98)

15.80 (6.89; 36.27)

− 8.4% (− 11.4%; − 5.3%)

< 0.001

PM hypertension

0.80 (0.80/0.80)

0.51 (0.48/0.58)

1.64 (1.42; 1.89)

34.5% (29.3%; 39.8%)

< 0.001

PM triglycerides

1 (NA/NA)

0.30 (NA/NA)

1.42 (1.34; 1.51)

70.0% (65.7%; 74.2%)

< 0.001

PM triglycerides w/o PM biochemistry

0.50 (NA/NA)

0.98 (NA/NA)

31.50 (6.65; 151.21)

1.4% (0.1%; 2.6%)

0.077

PM glucose

0.87 (0.82/0.94)

0.90 (0.92/0.88)

8.81 (6.41; 12.10)

7.9% (5.0; 10.8%)

< 0.001

  1. All results are evaluated comparing the PM definition or criterion to the AM definition and the corresponding criterion. Gender-specific sensitivity and specificity for triglycerides was not calculated due to restrictions from Statistics Denmark regarding disclosure of aggregated microdata (N < 3)
  2. AM ante mortem, CI confidence interval, MetS metabolic syndrome, PM post mortem, w/o without