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Table 5 Evaluation of the PM definition of the metabolic syndrome and individual criteria

From: Establishing post mortem criteria for the metabolic syndrome: an autopsy based cross-sectional study

  Sensitivity (male/female) Specificity (male/female) Likelihood ratio (95% CI) Difference PM vs. AM (95% CI) P value
PM definition MetS 0.63 (0.70/0.57) 0.93 (0.94/0.91) 9.27 (6.05; 14.19) 2.3% (− 0.7%; 5.2%) 0.175
PM cholesterol 0.29 (0.38/0.17) 0.98 (0.98/0.98) 15.80 (6.89; 36.27) − 8.4% (− 11.4%; − 5.3%) < 0.001
PM hypertension 0.80 (0.80/0.80) 0.51 (0.48/0.58) 1.64 (1.42; 1.89) 34.5% (29.3%; 39.8%) < 0.001
PM triglycerides 1 (NA/NA) 0.30 (NA/NA) 1.42 (1.34; 1.51) 70.0% (65.7%; 74.2%) < 0.001
PM triglycerides w/o PM biochemistry 0.50 (NA/NA) 0.98 (NA/NA) 31.50 (6.65; 151.21) 1.4% (0.1%; 2.6%) 0.077
PM glucose 0.87 (0.82/0.94) 0.90 (0.92/0.88) 8.81 (6.41; 12.10) 7.9% (5.0; 10.8%) < 0.001
  1. All results are evaluated comparing the PM definition or criterion to the AM definition and the corresponding criterion. Gender-specific sensitivity and specificity for triglycerides was not calculated due to restrictions from Statistics Denmark regarding disclosure of aggregated microdata (N < 3)
  2. AM ante mortem, CI confidence interval, MetS metabolic syndrome, PM post mortem, w/o without