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Table 2 Characteristics of patients with type 1 diabetes according to groups of renal function

From: Serum uric acid and renal function in patients with type 1 diabetes: a nationwide study in Brazil

Variables Groups p value
Normal renal function GFR ≥60 ml/min and albuminuria GFR < 60 ml/min
n = 1686 1170 246 270
Age, (year) 28.7 ± 11.7 28.1 ± 10.0 37.9 ± 11.7* p < 0.001
Gender, (% female) 631 (53.9) 125 (50.8) 186 (68.8)* p < 0.001
Duration of diabetes, (year) 14.1 ± 9.1 15.2 ± 7.5 20.8 ± 9.8* p < 0.001
Years of study, (year) 12.3 ± 3.9 11.9 ± 3.5 11.8 ± 3.8 p = 0.086
Insulin dose, (units/kg/day) 0.86 ± 0.36 0.94 ± 0.46* 0.79 ± 0.36* p < 0.001
Cigarette smoking, (%) 58 (5.0) 15 (6.1) 16 (5.9) p = 0.233
Hypertension, (%) 130 (11.1) 45 (18.3)* 119 (44)* p < 0.001
Dyslipidemia, (%) 203 (17.4) 51 (20.8) 105 (39)* p < 0.001
Systolic blood pressure (mmhg) 119.1 ± 14.1 124.2 ± 16.1* 129.5 ± 20.7* p < 0.001
Diastolic blood pressure (mmhg) 73.3 ± 9.4 78.1 ± 10.6* 79.6 ± 12.3* p < 0.001
BMI (kg/m2) 24.0 ± 4.0 24.1 ± 4.0 24.9 ± 4.3 p = 0.005
HbA1c (%) 8.9 ± 2.0 9.9 ± 2.5* 8.9 ± 2.0 p < 0.001
HbA1c (mmol/mol) 73.2 ± 22.2 84.8 ± 27.2* 73.5 ± 21.3 p < 0.001
Serum uric acid (mg/dl) 4.8 ± 1.4 5.2 ± 2.0* 6.5 ± 2.6* p < 0.001
  1. GFR Glomerular filtration rate (ml/min), SD standard deviation, y years, data are presented as number (percentage), mean ± SD. ANOVA was used for continuous variables and Chi square test for categorical variables
  2. * p < 0.05 vs Normal Renal function group