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Table 1 Comparison of data obtained at baseline and after 3–6 months of follow up in all three groups of patients

From: The effectiveness of lixisenatide as an add on therapy to basal insulin in diabetic type 2 patients previously treated with different insulin regimes: a multi-center observational study

Type of insulin regime (n)

Parameters

Baseline

Control visit

p value

Mean ± SD

Mean ± SD

Premix (50)

Weight (kg)

104 ± 14

99 ± 13

 0.003

BMI (kg/m2)

38.1 ± 3.1

36.0 ± 3.1

 0.039

Total daily insulin (IU)

53 ± 21

41 ± 12

< 0.001

Hba1c (%)

8.4 ± 1.2

7.6 ± 0.9

< 0.001

FBG (mmol/l)

10.1 ± 2.4

7.7 ± 1.8

< 0.001

PPG (mmol/l)

10.8 ± 2.5

8.7 ± 2

< 0.001

Basal oral (46)

Weight (kg)

109 ± 12

104 ± 11

 0.003

BMI (kg/m2)

38.7 ± 3.3

38.6 ± 10

NS

Total daily insulin (IU)

35 ± 14

37 ± 11

NS

Hba1c (%)

8.5 ± 0.9

7.6 ± 0.7

< 0.001

FBG (mmol/l)

8.3 ± 2.4

7.2 ± 1.6

 0.009

PPG (mmol/l)

11.4 ± 2.1

8.4 ± 1.7

< 0.001

Basal bolus (15)

Weight (kg)

107 ± 19

98 ± 14

< 0.001

BMI (kg/m2)

36.0 ± 1

33.8 ± 1.1

 0.039

Total daily insulin (IU)

71 ± 27

50 ± 24

 0.006

Hba1c (%)

9.6 ± 1.8

7.5 ± 0.9

< 0.001

FBG (mmol/l)

10.3 ± 3

7.6 ± 1.4

< 0.001

PPG (mmol/l)

12.4 ± 2.9

9.2 ± 2.5

< 0.001

  1. BMI body mass index, FPG fasting plasma glucose, PPG postprandial plasma glucose