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Table 2 GRADE quality assessment

From: The effects of exercise on vascular endothelial function in type 2 diabetes: a systematic review and meta-analysis

Quality assessment No of patients Effect Quality Importance
No of studies Design Risk of bias Inconsistency Indirectness Imprecision Other considerations Exercise Control Relative (95% CI) Absolute
Flow-mediated dilation
 8 Randomised trials No serious risk of bias Seriousa No serious indirectness No serious imprecision None 196 110 SMD 0.41 higher
(0.21 higher to 0.62 higher)
Ο
Moderate
Critical
Shear rate area under the curve
 3 Randomised trials No serious risk of bias Seriousa No serious indirectness Very seriousb,c None 78 15 SMD 0.05 lower
(0.43 lower to 0.34 higher)
ΟΟ
Low
Critical
Baseline brachial artery diameter
 7 Randomised trials No serious risk of bias No serious inconsistency No serious indirectness Seriousc None 171 95 SMD 0.04 lower
(0.25 lower to 0.17 higher)
Ο
Moderate
Critical
Body mass index
 7 Randomised trials No serious risk of bias No serious inconsistency No serious indirectness Seriousc None 183 95 SMD 0.13 lower
(0.34 lower to 0.08 higher)
Ο
Moderate
Important
  1. aQuite different inflation pressure between studies
  2. bOutcome based on only three studies
  3. c95% confidence interval includes zero