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Table 4 Scores of OHA-Q ver. 2

From: Dapagliflozin improves treatment satisfaction in overweight patients with type 2 diabetes mellitus: a patient reported outcome study (PRO study)

Items

Baseline

Week 14

Change

P value

1. Missed dose

2.05 ± 0.77

2.21 ± 0.73

0.16 ± 0.65

< 0.001

2. Difficulty swallowing

2.62 ± 0.59

2.71 ± 0.54

0.09 ± 0.55

0.026

3. Carrying and preparing for taking the agent

2.29 ± 0.78

2.22 ± 0.83

− 0.07 ± 0.73

0.20

4. People around the patient

2.31 ± 0.85

2.31 ± 0.82

0.00 ± 0.60

1.00

5. Following the meal schedule

1.81 ± 0.92

1.81 ± 0.92

− 0.01 ± 0.79

0.93

6. Interval between taking the agent and a meal

1.77 ± 0.94

1.75 ± 0.90

− 0.02 ± 0.88

0.80

7. Compliance with treatment schedule

1.90 ± 0.92

1.87 ± 0.89

− 0.03 ± 0.80

0.59

8. Number of doses

2.23 ± 0.77

2.36 ± 0.71

0.13 ± 0.73

0.018

9. Taking the agent at a place other than home

2.10 ± 0.75

2.23 ± 0.73

0.13 ± 0.75

0.016

10. Desire to continue the treatment

1.77 ± 0.81

1.89 ± 0.84

0.12 ± 0.85

0.06

11. Rumbling stomach

1.95 ± 0.86

2.04 ± 0.87

0.09 ± 0.93

0.19

12. Diarrhea

2.08 ± 0.85

2.29 ± 0.85

0.21 ± 0.94

0.003

13. Constipation

2.05 ± 0.87

2.00 ± 0.99

− 0.05 ± 0.86

0.40

14. Increase in body weight

0.86 ± 0.91

1.48 ± 1.04

0.62 ± 1.01

< 0.001

15. Tendency to become hungry easily

1.73 ± 0.83

1.74 ± 0.82

0.02 ± 0.82

0.79

16. Nausea

1.89 ± 0.95

2.13 ± 0.85

0.24 ± 0.87

< 0.001

17. Bodily swelling

1.83 ± 0.93

2.13 ± 0.85

0.30 ± 0.82

< 0.001

18. Hypoglycemia

2.00 ± 0.78

2.11 ± 0.75

0.11 ± 0.74

0.040

19. Frequent urination

1.78 ± 0.84

1.57 ± 0.89

− 0.20 ± 0.94

0.004

20. Thirst

1.74 ± 0.79

1.66 ± 0.83

− 0.07 ± 0.86

0.24

21. Discomfort with urination or genital pruritus

2.22 ± 0.83

2.19 ± 0.82

− 0.03 ± 0.89

0.62

22. Glycemic control

1.43 ± 0.81

1.80 ± 0.71

0.37 ± 0.80

< 0.001

23. Satisfaction with the current agent

1.88 ± 0.68

2.10 ± 0.58

0.21 ± 0.70

< 0.001

Subscale 1: Treatment convenience

19.09 ± 4.78

19.48 ± 4.97

0.39 ± 3.02

0.08

Subscale 2: Somatic symptom

20.14 ± 5.28

21.36 ± 5.42

1.22 ± 4.41

< 0.001

Subscale 3: Satisfaction

5.09 ± 1.77

5.78 ± 1.67

0.70 ± 1.72

< 0.001

Total

44.31 ± 9.43

46.62 ± 9.83

2.31 ± 6.60

< 0.001

  1. Data are shown as mean ± SD; n = 188; subscale 1: treatment convenience (score range 0–27); subscale 2: somatic symptom (score range 0–33); subscale 3: satisfaction (score range 0–9); total (score range 0–69)
  2. OHA-Q Oral Hypoglycemic Agent-Questionnaire
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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