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Table 4 Scores of OHA-Q ver. 2

From: Dapagliflozin improves treatment satisfaction in overweight patients with type 2 diabetes mellitus: a patient reported outcome study (PRO study)

Items Baseline Week 14 Change P value
1. Missed dose 2.05 ± 0.77 2.21 ± 0.73 0.16 ± 0.65 < 0.001
2. Difficulty swallowing 2.62 ± 0.59 2.71 ± 0.54 0.09 ± 0.55 0.026
3. Carrying and preparing for taking the agent 2.29 ± 0.78 2.22 ± 0.83 − 0.07 ± 0.73 0.20
4. People around the patient 2.31 ± 0.85 2.31 ± 0.82 0.00 ± 0.60 1.00
5. Following the meal schedule 1.81 ± 0.92 1.81 ± 0.92 − 0.01 ± 0.79 0.93
6. Interval between taking the agent and a meal 1.77 ± 0.94 1.75 ± 0.90 − 0.02 ± 0.88 0.80
7. Compliance with treatment schedule 1.90 ± 0.92 1.87 ± 0.89 − 0.03 ± 0.80 0.59
8. Number of doses 2.23 ± 0.77 2.36 ± 0.71 0.13 ± 0.73 0.018
9. Taking the agent at a place other than home 2.10 ± 0.75 2.23 ± 0.73 0.13 ± 0.75 0.016
10. Desire to continue the treatment 1.77 ± 0.81 1.89 ± 0.84 0.12 ± 0.85 0.06
11. Rumbling stomach 1.95 ± 0.86 2.04 ± 0.87 0.09 ± 0.93 0.19
12. Diarrhea 2.08 ± 0.85 2.29 ± 0.85 0.21 ± 0.94 0.003
13. Constipation 2.05 ± 0.87 2.00 ± 0.99 − 0.05 ± 0.86 0.40
14. Increase in body weight 0.86 ± 0.91 1.48 ± 1.04 0.62 ± 1.01 < 0.001
15. Tendency to become hungry easily 1.73 ± 0.83 1.74 ± 0.82 0.02 ± 0.82 0.79
16. Nausea 1.89 ± 0.95 2.13 ± 0.85 0.24 ± 0.87 < 0.001
17. Bodily swelling 1.83 ± 0.93 2.13 ± 0.85 0.30 ± 0.82 < 0.001
18. Hypoglycemia 2.00 ± 0.78 2.11 ± 0.75 0.11 ± 0.74 0.040
19. Frequent urination 1.78 ± 0.84 1.57 ± 0.89 − 0.20 ± 0.94 0.004
20. Thirst 1.74 ± 0.79 1.66 ± 0.83 − 0.07 ± 0.86 0.24
21. Discomfort with urination or genital pruritus 2.22 ± 0.83 2.19 ± 0.82 − 0.03 ± 0.89 0.62
22. Glycemic control 1.43 ± 0.81 1.80 ± 0.71 0.37 ± 0.80 < 0.001
23. Satisfaction with the current agent 1.88 ± 0.68 2.10 ± 0.58 0.21 ± 0.70 < 0.001
Subscale 1: Treatment convenience 19.09 ± 4.78 19.48 ± 4.97 0.39 ± 3.02 0.08
Subscale 2: Somatic symptom 20.14 ± 5.28 21.36 ± 5.42 1.22 ± 4.41 < 0.001
Subscale 3: Satisfaction 5.09 ± 1.77 5.78 ± 1.67 0.70 ± 1.72 < 0.001
Total 44.31 ± 9.43 46.62 ± 9.83 2.31 ± 6.60 < 0.001
  1. Data are shown as mean ± SD; n = 188; subscale 1: treatment convenience (score range 0–27); subscale 2: somatic symptom (score range 0–33); subscale 3: satisfaction (score range 0–9); total (score range 0–69)
  2. OHA-Q Oral Hypoglycemic Agent-Questionnaire