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Table 2 Distribution of the COMT Val108/158Met and DBH-1021C/T genotypes in patients with type 2 diabetes (T2DM patients) and healthy controls, and in subjects subdivided according to gender

From: The influence of dopamine-beta-hydroxylase and catechol O-methyltransferase gene polymorphism on the efficacy of insulin detemir therapy in patients with type 2 diabetes mellitus

 

COMT Val108/158Met

DBH-1021C/T

T2DM/controls

AA

AG

GG

CC

CT

TT

T2DM patients

39 (21.1%)

101 (54.6%)

45 (24.3%)

113 (61.1%)

64 (34.6%)

8 (4.3%)

Healthy controls

36 (23.1%)

80 (51.3%)

40 (25.6%)

94 (60.3%)

56(35.9%)

6 (3.8%)

χ2 test

χ2 = 0.389; df = 2; p = 0.824

χ2 = 0.097; df = 2; p = 0.952

T2DM women

25 (21.7%)

61 (53.1%)

29(25.2%)

68 (59.1%)

42 (36.5%)

5 (4.4%)

Healthy women

27 (26%)

49 (47.1%)

28 (26.9%)

63 (60.6%)

36 (34.6%)

5 (4.8%)

χ2 test

χ2 = 0.853; df = 2; p = 0.653

χ2 = 0.100; df = 2; p = 0.951

T2DM men

14 (20%)

40 (57.1%)

16 (22.9%)

45 (64.3%)

22 (31.4%)

3 (4.28%)

Healthy men

9 (17.3%)

31 (59.6%)

12 (23.1%)

31 (59.6%)

20 (38.5%)

1 (1.9%)

χ2 test

χ2 = 0.147; df = 2; p = 0.929

χ2 = 1.041; df = 2; p = 0.594