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Table 3 Sensitivity analysis

From: Effects of pioglitazone therapy on blood parameters, weight and BMI: a meta-analysis

Excluded study Pooled WMD for FPG (mmol/l) Pooled WMD for HbA1c (%) Pooled WMD for total cholesterol (mmol/l) Pooled WMD for LDL (mmol/l) Pooled WMD for HDL (mmol/l) Pooled WMD for triglycerides (mmol/l) Pooled WMD for BMI (kg/m2) Pooled WMD for weight (kg)
Berhanu et al. [13] − 1.678 (− 2.128; − 1.228) − 1.041 (− 1.248; − 0.835) 0.091 (− 0.111; 0.294) 0.051 (− 0.042; 0.143) 0.197 (0.067; 0.327) − 0.300 (− 0.653; 0.054) 1.148 (0.368; 1.928) 1.747 (0.657; 2.837)
Belfort et al. [14] − 1.568 (− 2.016; − 1.121) − 1.105 (− 1.312; − 0.897) 0.121 (− 0.011; 0.253) 0.054 (− 0.035; 0.144) 0.199 (0.068; 0.329) − 0.267 (− 0.614; 0.080)   
DeFronzo et al. [16] − 1.608 (− 2.284; − 0.933)     0.172 (0.131; 0.213) − 0.136 (− 0.244; − 0.028) 1.091 (0.060; 2.121) 1.396 (0.559; 2.233)
DeFronzo et al. [17] − 1.642 (− 2.152; − 1.131)       1.026 (0.108; 1.944)  
Mattoo et al. [15] − 1.560 (− 2.005; − 1.114) − 1.115 (− 1.324; − 0.906)   0.086 (0.001; 0.171) 0.196 (0.065; 0.327)    
Rosenstock et al. (15 mg) [18] − 1.517 (− 1.962; − 1.071) − 1.093 (− 1.316; − 0.870)   0.043 (− 0.056; 0.143) 0.191 (0.059; 0.323) − 0.308 (− 0.665; 0.049)   
Rosenstock et al. (30 mg) [18] − 1.464 (− 1.902; − 1.026) − 1.068 (− 1.295; − 0.842)   0.046 (− 0.077; 0.169) 0.186 (0.054; 0.318) − 0.286 (− 0.649; 0.077)   
Davidson et al. (30 mg) [19] − 1.526 (− 1.971; − 1.080) − 1.074 (− 1.301; − 0.847)   0.039 (− 0.060; 0.137) 0.185 (0.051; 0.319) − 0.296 (− 0.687; 0.095)   
Davidson et al. (45 mg) [19] − 1.470 (− 1.905; − 1.036) − 1.048 (− 1.258; − 0.838)   0.039 (− 0.059; 0.137) 0.177 (0.043; 0.312) − 0.293 (− 0.689; 0.103)   
Goldberg et al. [3] − 1.520 (− 1.954; − 1.086) − 1.122 (− 1.325; − 0.920) 0.077 (− 0.029; 0.183) 0.024 (− 0.057; 0.104) 0.196 (0.066; 0.325) − 0.228 (− 0.585; 0.130)   1.708 (0.364; 3.053)
Panikar et al. (7.5 mg) [22]   − 1.083 (− 1.288; − 0.877)      1.150 (0.385; 1.915) 1.915 (0.786; 3.043)
Panikar et al. (15 mg) [22]   − 1.084 (− 1.290; − 0.878)      1.137 (0.373; 1.902) 1.873 (0.743; 3.004)
Panikar et al. (30 mg) [22]   − 1.084 (− 1.289; − 0879)      1.120 (0.356; 1.884) 1.829 (0.649; 2.963)
Xu et al. [20] − 1.509 (− 1.950; − 1.067) − 1.049 (− 1.261; − 0.837) 0.199 (0.124; 0.275) 0.067 (− 0.024; 0.158) 0.192 (0.059; 0.326) − 0.276 (− 0.633; 0.082) 1.412 (1.335; 1.488) 2.097 (1.101; 3.092)
Yoshii et al. [25]     0.088 (0.003; 0.172) 0.196 (0.065; 0.327)    
Bolli et al. [12] − 1.538 (− 1.984; − 1.092) − 1.045 (− 1.254; − 0.836)       1.613 (0.341; 2.885)
Kodama et al. [23]   − 1.141 (− 1.339; − 0.943)   0.057 (− 0.033; 0.148) 0.194 (0.063; 0.324)    1.786 (0.689; 2.884)
Shah et al. [24]   − 1.138 (− 1.334; − 0.941)      1.054 (0.132; 1.977) 1.711 (0.619; 2.803)
Gerber et al. (30 mg) [21] − 1.462 (1.857; − 1.067) − 1.086 (− 1.290; − 0.882) 0.124 (− 0.001; 0.249) 0.055 (− 0.034; 0.143) 0.192 (0.065; 0.320) − 0.263 (− 0.595; 0.068)   1.728 (0.625; 2.830)
Gerber et al. (30/45 mg) [21] − 1.516 (− 1.956; − 1.075) − 1.086 (− 1.290; − 0.882) 0.123 (− 0.003; 0.248) 0.055 (− 0.033; 0.143) 0.192 (0.065; 0.319) − 0.266 (− 0.597; 0.065)   1.728 (0.627; 2.828)
Gerber et al. (45 mg) [21] − 1.545 (− 1.993; − 1.097) − 1.087 (− 1.290; − 0.883) 0.123 (− 0.003; 0.249) 0.055 (− 0.033; 0.143) 0.195 (0.066; 0.323) − 0.267 (− 0.599; 0.065)   1.729 (0.632; 2.827)