TY - JOUR AU - Filipova, Elena AU - Uzunova, Katya AU - Kalinov, Krassimir AU - Vekov, Toni PY - 2017 DA - 2017/11/14 TI - Effects of pioglitazone therapy on blood parameters, weight and BMI: a meta-analysis JO - Diabetology & Metabolic Syndrome SP - 90 VL - 9 IS - 1 AB - Type 2 diabetes mellitus (T2DM) is one of the most common diseases worldwide and insulin insufficiency and insulin resistance are two main metabolic issues connected with it. The dyslipidemia associated with insulin resistance and T2DM is characterized by higher triglycerides (TGs), higher very-low-density lipoprotein cholesterol and lower apo A1. Pioglitazone, a member of the thiazolidinedione class, with a proven antihyperglycemic effect, is known to positively influence insulin sensitivity and β-cell function and to have the potential to alter the lipid profile. SN - 1758-5996 UR - https://doi.org/10.1186/s13098-017-0290-5 DO - 10.1186/s13098-017-0290-5 ID - Filipova2017 ER -