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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Association of body mass index and visceral fat with aortic valve calcification and mortality after transcatheter aortic valve replacement: the obesity paradox in severe aortic stenosis

Fig. 2

Relationship between BMI and visceral abdominal fat with all-cause mortality. Fractional polynomials analysis applied to univariate cox regression showed that the risk of all-cause mortality decreased with the increment of BMI (a). Kaplan–Meier curves for all-cause mortality by categories of BMI did not differ significantly but normal weight and obese patients tended to have higher incidence of death compared with the overweight (b). Univariate Cox regression using fractional polynomials showed an increased risk of death with the increment of VAF (c), but this association seemed to differ according to the patient BMI and different mortality rates curves were obtained within the non-obese (d1) and obese (d2) groups. We further combined BMI with VAF-categories, and we observed that the cumulative incidence of all-cause death was lowest in the obese that showed low amount of VAF (blue colour code) but high if VAF was high (yellow colour code); in the non-obese, low VAF identified clusters of patients at higher risk of death (e). AVC aortic valve calcification, BMI body mass index, SAF subcutaneous abdominal fat, VAF visceral abdominal fat

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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