Table 2 Neutrophil subsets (average %) by cohort of Visit 1 and Visit 2
Cohort | ||||||
|---|---|---|---|---|---|---|
Neutrophil subset | Poorly-controlled diabetes mellitus (N = 14) | Well-controlled diabetes mellitus (N = 12) | Morbid obesity (N = 12) | Obese with metabolic syndrome (N = 20) | Obese without metabolic syndrome (N = 20) | Control (N = 12) |
“Normal” (CD16bright/CD62Lbright) | ||||||
N, % RSD | 14, 3.73 | 12, 7.54 | 12, 18.10 | 20, 9.11 | 20, 16.83 | 12, 6.85 |
Mean, median | 91.2, 92.3 | 90.3, 91.9 | 81.1, 84.0 | 86.3, 88.4 | 84.0, 89.9 | 88.5, 89.0 |
95% CI | 84.2, 98.9 | 76.5, 106.5 | 54.7, 120.5 | 71.3, 104.4 | 59.2, 119.2 | 76.1, 102.9 |
“Suppressors” (CD16bright/CD62Ldim) | ||||||
N, % RSD | 14, 107.5 | 12, 135.3 | 12, 150.9 | 20, 143.6 | 20, 213.2 | 12, 124.2 |
Mean, median | 2.5, 2.5 | 2.4, 2.2 | 5.9, 6.1 | 3.4, 3.2 | 4.2, 3.6 | 2.2, 1.5 |
95% CI | 0.4, 16.9 | 0.3, 22.7 | 0.5, 65.1 | 0.4, 31.1 | 0.3, 65.1 | 0.3, 18.5 |
“Killer” (CD16dim/CD62Lbright) | ||||||
N, % RSD | 14, 82.83 | 12, 83.71 | 12, 60.22 | 20, 78.80 | 20, 55.68 | 12, 43.27 |
Mean, median | 2.8, 2.7 | 3.1, 3.1 | 4.9, 5.3 | 4.7, 5.1 | 3.0, 3.2 | 4.7, 4.9 |
95% CI | 0.6, 13.3 | 0.6, 15.5 | 1.5, 16.8 | 1.1, 20.2 | 1.0, 8.9 | 1.9, 11.7 |
%CD47+ | ||||||
N, % RSD | 14, 0.03 | 12, 0.44 | 12, 0.04 | 20, 0.23 | 20, 0.04 | 12, 0.01 |
Mean, median | 100.0, 100.0 | 99.8, 100.0 | 100.0, 100.0 | 99.9, 100.0 | 100.0, 100.0 | 100.0, 100.0 |
95% CI | 99.9, 100.0 | 98.8, 100.7 | 99.9, 100.1 | 99.4, 100.4 | 99.9, 100.1 | 100.0, 100.0 |
CD47 MFI | ||||||
N, % RSD | 14, 25.13 | 12, 48.26 | 12, 18.40 | 20, 17.28 | 20, 19.60 | 12, 19.80 |
Mean, median | 18,462, 16,709 | 15,558, 16,598 | 19,060, 19,857 | 16,627, 17,062 | 17,226, 16,118 | 18,164, 17,718 |
95% CI | 10,817, 31,510 | 5684, 42,590 | 12,757, 28,477 | 11,612, 23,809 | 11,475, 25,860 | 11,797, 27,967 |