Fig. 2

The proposed relation between nutrition and bone mass. GIP, and possibly GLP-1 and GLP-2, may link nutrient ingestion to the suppression of bone resorption and the stimulation of bone formation. This link is likely because both osteoblasts and osteoclasts express receptors for incretins, which positively regulate bone metabolism IGF-1 insulin-like growth factor-1, GIP glucose-dependent insulinotropic peptide, GLP-2 glucagon-like peptide-2, PTH parathyroid hormone. Modified from Reid et al. [47]