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Fig. 5 | Diabetology & Metabolic Syndrome

Fig. 5

From: The promotion of nephropathy by Porphyromonas gingivalis lipopolysaccharide via toll-like receptors

Fig. 5

Expression of type 1 collagen in the STZ-induced type 1 diabetic mouse glomeruli. HE staining (upper lane), immunostaining for type 1 collagen (green, middle lane), and merged (lower lane) immunostaining for type 1 collagen (green) and podoplanin (red), and DAPI staining of nuclei (blue). The type 1 collagen expression locates between podocytes immunostained by anti-podoplanin. Expression of type 1 collagen is observed in the non-diabetic ICR mice (ICR) and non-diabetic ICR mice administered Pg-LPS (LPS), and is stronger in the STZ-induced type 1 diabetic mouse glomeruli. The expression of type 1 collagen is stronger in the diabetic mice with Pg-LPS (STZ-LPS) than in the diabetic mouse not administered Pg-LPS, and the level is slightly lower in the diabetic mice administered with Pg-LPS and eritoran (eritoran). Bars: 20 μm

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