Table 3 ORs for prolonged QTc interval according to ISI_Matsuda quartiles (95% CI)

n

733

727

730

737

–

Model 1

4.45 (3.41–5.81)

2.50 (1.89–3.30)

1.59 (1.19–2.13)

1-Reference

<0.001

Model 2

4.29 (3.25–5.65)

2.46 (1.85–3.26)

1.59 (1.18–2.14)

1-Reference

<0.001

Model 3

3.58 (2.62–4.88)

2.12 (1.56–2.89)

1.55 (1.13–2.14)

1-Reference

<0.001

Model 4

3.12 (2.24–4.34)

2.08 (1.50–2.87)

1.50 (1.07–2.11)

1-Reference

<0.001

Model 5

3.11 (2.23–4.34)

2.09 (1.51–2.88)

1.53 (1.09–2.14)

1-Reference

<0.001